自拟清肝养阴方对甲状腺功能亢进症合并肝损害的临床探究.pdfVIP

提 要 目的:观察自拟清肝养阴方对甲状腺功能亢进症（本文所涉及的甲亢患者主要指 弥漫性毒性甲状腺肿）合并肝损害，中医辨证属肝火旺、血瘀痰凝型的临床疗效。方 法:将临床诊断为甲状腺功能亢进症合并肝损害属肝火旺、血瘀痰凝型的66例患者随 机分为两组，其对照组33例，给予足量他巴唑、心得安及维生素C、天晴甘平治疗； 治疗组33例，予以自拟清肝养阴方、维生素C、天晴甘平合对照组一半剂量的他巴唑， 加心得安治疗，总共观察三个疗程（一个月为一疗程）。结果:研究结果显示治疗组改 善肝功能、甲状腺功能等实验室指标优于对照组（P0.05）,改善甲亢性肝损害患者 的临床症状体征亦优于对照组（P0.05），并可改善血清甲状腺球蛋白抗体（TG-Ab） 及甲状腺过氧化物酶抗体（TPO-Ab）指标，对甲状腺突眼及甲状腺肿亦有改善。结论: 临床研究表明，基本保肝治疗加用自拟清肝养阴方在保肝降酶、提高抗甲状腺激素 （ATD）治疗方面疗效显著，并有可调节机体免疫功能，有效改善患者临床症状体征， 改善甲亢性突眼和甲状腺肿大，避免或减少西药不良反应等良好效果, 值得进一步研 究推广。 关键词 自拟清肝养阴方；甲亢合并肝损害；肝火旺，血瘀痰凝型；临床研究 Clinical research on the Nourish Yin to clear liver from thyroid function party of liver damage hyperthyroidism merger Speciality: Internal Medicine of TCM Author: Chen Shasha Tutor: Professor Wang Liqin Abstract Object: To study the nourish Yin party of clear liver thyroid function of hyperthyroidism (involved patients with hyperthyroidism paper mainly refers to the diffuse toxic strumous) merger of liver damage, TCM syndrome differentiation flourish, blood stasis suffered the clinical curative effect of TanNing type. Methods: Will clinical diagnosis for thyroid function of liver damage suffered hyperthyroidism merger leavened, blood stasis TanNing type of 66 cases were randomly divided into two groups ，The control group (n = 33) give enough he ba thiazole, propranolol and vitamin C, sunny GanPing treatment; The treatment group (n = 33) since intends to clear liver to nourish Yin square, vitamin C, sunny group GanPing close half doses of his ba, add propranolol paclobutrazol treatment. A total of three treatments (a month observed for one period of treatment). Result: Research result shows that the treatment group improve liver function, such as thyroid