异丙酚加芬太尼辅助硬膜外麻醉在小儿阑尾手术中的应用.pdfVIP

2008年2月第5卷第6期 · 临床研究 · 异丙酚加芬太尼辅助硬膜外麻醉 在小儿阑尾手术中的应用 王建科 (湖北省当阳市人民医院麻醉科，湖北当阳 44410o) 【摘要】目的：研究异丙酚加芬太尼辅助硬膜外麻醉在4,JL阑尾手术中的应用，并与咪唑安定加氯胺酮进行比较。方 法：将60例阑尾炎患儿随机分为两组，I组采用异丙酚加芬太尼，Ⅱ组采用咪唑安定加氯胺酮，分别记录麻醉前、麻 醉后l、5、10、15 min的RR(呼吸频率)、HR(心率)、Sp02(氧饱和度)、MAP(平均动脉压)、术后清醒时间(睁眼和清楚应 答)、术后24 h内恶心、呕吐的发生率。结果：两组麻醉后 1、5、10、15 min，HR、RR变化有显著性差异(Pl0．05)，SpO 、 MAP无显著差异，I组术后无躁动，恶心、呕吐1例，Ⅱ组术后躁动4例，恶心、呕吐6例。结论：异丙酚加芬太尼辅助 硬膜外麻醉在s],JL阑尾手术中比氯胺酮加咪唑安定更具优越性。 【关键词1异丙酚；芬太尼；硬膜外麻醉 【中图分类号】R614 【文献标识码】A 【文章编号】1673—7210(2008)02(c)一039—02 The clinical application of propofol combined with fentanyl to assist epidural anesthesia in pedO—appendix intraoperative WANG Jian—ke (Department of Anesthesiology，the Peoples Hospital of Dangyang，Hubei Province，Dangyang 444100，China) [Abstract]Objective：To study the clinical application of propofol combined with fentanyl to assist epidural anesthesia in pedo—appendix intraoperative，and compared with midazolam combined with ketamine．Methods：To divide the sixty appen． dicitis children into two groups，propofol combined with fentanyl and midazolam combined with ketamine，record the 1 min， 5 min，10 min，15 min RR，HR，Sp02，MAP，after—operative consciousness time，the rate of nausea and vomitory in the fore— anesthesia and after—anesthesia．Results：The 1,5，10，15 min RR and HR in the after—anesthesia of th two groups indicated significant difference(P0．os)，Sp02 and MAP indicated no significant difference．There has been no restlessness in the group of propofol combined with fentanyl after operation，but four in the group of midazolam comb ined with ketamine ． Th e rate of nau