交沙霉素治疗93例牙周病疗效观察.docVIP

交沙霉素治疗93例牙周病疗效观察【摘要】目的 研究治疗牙周病的方案及其它的有效性、安全性和经济性。方法 将我院口腔科就诊的186例牙周病患者，随机分为AB两组，两组均排除患有糖尿病患者，排除孕妇和哺乳期妇女；两组治疗时间均为7天，A组93例应用交沙霉素＋甲硝唑＋维生素B6，B组93例应用头孢他美酯＋甲硝唑＋维生素B6，两组患者每日常规保持口腔卫生维护。结果 A组显效72例，有效11例，无效10例；B组显效58例，有效21例，无效14例；A组有效率89.2%，B组有效率85%。AB两组药物不良反应的发生率分别为8.6%、9.7%，A组的药品费比B组少43.40元。结论 牙周病选择A组的治疗方案是可行的，是有效的。 【关键词】交沙霉素 头孢他美酯 治疗 牙周病 疗效 中图分类号：R781.4文献标识码：A文章编号：1005-0515（2011）4-008-03 The Efficacy of 93 Periodontal PatientsTreated.with.Josamycin Zhang Yongmei （Shehong Peoples Hospital, Sichuan,629200） 【Abstract】Objective To find the way of efficacy, safety and economy in treatment of periodontal disease. Methods Firstly, 186 cases of periodontal patients in our Dental department were randomly divided into Group A and Group B, of which diabetes, pregnant and lactating women were excluded. The following week, 93 patients in Group A were kept giving drugs as Josamycin , Metronidazole and Vitamin B6, 93 patients in Group B were kept giving drugs as Cefetametester, Metronidazole and Vitamin B6, and kept all the patients oral hygiene routine maintenance. Results 72 patients in Group A took effect, 11 patients took good effect, and 10 had no effect. 58 patients in Group B took effect, 21 patients took good effect, and 14 had no effect. The effective rate in Group A was 89.2%; in Group B was 85%. The incidence of adverse drug reactions were 8.6%, 9.7% in both groups. The cost in Group A was 43.40 Yuan less than Group B. Conclusion Thus, the periodontal treatment of Group A is feasible, and effective. 【Key words】osamycin Cefetametester treatment Periodontal, efficacy 口腔是人体的一个非常重要而又特殊的器官，口腔健康是人体健康的重要组成部分，口腔疾病与全身系统性疾病存在某种关联[1]。牙周病是发生在牙齿周围支持组织的慢性进行性破坏性疾病，牙周病是口腔内科的常见病、多发病，牙周病临床主要表现有牙龈呈深红色、肿胀、易出血、牙周脓肿、牙齿松动等。本文应用交沙霉素治疗牙周病93例，取得了较好的疗效，就此作一简要报道。 1 资料与方法 1.1 临床资料 2010年1月至2011年1月，来我院口腔科就诊的186例牙周病患者。男性103例，女性83例，年龄最大的72岁，最小的19岁，平均年龄42岁。其中学生13例、农民83例、城镇居民59例，机关干部31例。病程最短7天，最长13年。 1.2 方法 随机将牙周病患者分为AB两组，两组牙周病患者经过医师检查，排除患有糖尿病患者，排除孕妇和哺乳期妇女。A组93例，其中牙龈发红、不适20例、牙龈肿