代谢综合征基本危险因素及冠脉病变相关性探究.docVIP

代谢综合征基本危险因素及冠脉病变相关性探究摘要：目的：探讨代谢综合征不同分组与冠状动脉狭窄程度的 相关关系。方法：回顾性分析行冠脉造影的患者968例，所有患者均测体重指数、非同日血 压、血脂脂蛋白谱、空腹血糖和糖负荷后2h血糖；按照中华医学会糖尿病学会的标准，将代 谢综合征患者的高血压、高血糖、高血脂及肥胖基本因素中3个或4个因素进行不同分组；冠 状动脉病变程度采用Gensini积分。结果：男性较女性冠心病的患病率高；随着年龄的增长 ，冠脉病变的程度加重；4个因素组合以高血压、高血糖和脂代谢紊乱的组合冠脉病变的程 度最重。结论：代谢综合征合并冠心病存在病变范围广，病变程度高的特点；基本因素越多 及高血压、高血糖和脂代谢紊乱的组合冠脉病变的程度较重，因此需要更积极的干预治疗。 关键词：代谢综合征;冠状动脉疾病;危险因素 中图分类号： R543?3；R589 文献标识码： A 文章编号： 1008-2409(2008)05-0896-03 Relation between the risk factors of metabolic syndrome and coronary artery dise ase/LIANG Ling， ZHU li-guang∥Guilin Second People’s Hospital of Gu ilin City, Guilin 541001, China Abstract:Objective:To explore the relation between the differentgrouping of metabolic syndrome and the degree of coronary stenosis.Methods: Retr ospective analysis of angiographic coronary artery disease of 968 patients was c arried out, whose body mass index (BMI), blood pressure of several days, blood f a t lipoprotein, fasting glucose (FG) and two hours after taking glucose orally (P G)were measured. According to the standard of Chinese Medical Association Diabete s Society, every 3 or 4 factors of hypertension, hyperglycaemia, hyperlipidemiaand obesity of the patients with metabolic syndrome were grouped. The degree ofcoronary disease was determined by Gensini integral. Results: There was a highe r incidence for male to h ave coronary than for female. With aging, there was a higher degree of coronaryd isease. The composite coronary disease with the group of 4 factors , hypertensio n, hyperglycaemia and lipid metabolism disorder were the most serious. Concluti on:There is a higher degree and extent of disease about metabolic syndrome with co ronary. The more basic factors, the higher the degree of composite coronary dise ase of hypertension, hyperglycaemia and lipid metabolism disorder. In this way,more active intervention treatment should be needed. Key words:metabolic syndrome; coronary heart disease； high risk fac tor 随着社会经济的发展、人们生活水平的提高和生活方式的改变，高血压、