周传农修改-中国试验动物学报.DOCVIP

研究报告 先天性白内障大鼠的繁殖性能及其生长发育 田小芸， 尤金炜， 董 敏， 许龙祥， 赵志刚， 方 天， 恽时锋 （南京军区南京总医院比较医学科，南京 210002） [摘要] 目的 了解先天性白内障大鼠的生物学特性。方法 用原种群繁殖扩群，每组选用10对大鼠进行繁殖实验，观察繁殖性能及仔鼠的生长发育。结果 白内障大鼠组、小眼白内障组与正常对照组间的产仔数和离乳数均无显著性差异（p0.05）0.05）0.01））） [关键词] 先天性白内障，大鼠，繁殖，生长发育 【中图分类号】R33【文献标识码】A【文章编号】1671-7856（201）-0000-00 Doi:10.3969/j.issn.1671-7856.2013.010.000 Reproductive performance, growth and development of rats with congenital cataract TIAN Xiao-yun, NOU Jing -wei, Dong-Min, XU long-xiang, ZHAO zhi-gang, FANG Tian,YUN Shi-feng (Department of Comparative Medicine, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China) [Abstract] Objective To explore the biological characteristics of rats with congenital cataract. Methods To expand the populations by breeding with the original group, 10 pairs of rats were [基金项目]南京总医院基金资助，编号：2011001。 [作者简介]田小芸（1965-），女，硕士，副主任技师，研究方向：，tianxiaoyun838@[通讯作者] 恽时锋（1965-），男，博士，主任技师，研究方向：o observe the reproductive performance and growth and development of the offsprings. Results There were no significant differences in both the birth rate and the weaning number between the normal control group and cataract and microphthalmos cataract groups (P0.05). Compared with the other two groups, the cataract group had heavier body weight at the second week after birth. In comparison between males of different groups, the cataract group growed faster at first two weeks after birth and the difference in body weight was more obvious at fourth week after birth (P0.01). In comparison between sexes, there was significant different difference in body weight between male and female rats in the cataract group and the control group at the fifth week after birth (P0.01), while the microphthalmos cataract group had significant differences at the sixth week (P0.01). Conclusion Cataract gene in rats do not affect their reproductive rate, while there is certain effect on the growth of pups. [Key words] Co