聚丙烯酰胺水凝胶注射隆乳后感染菌群研究.docVIP

聚丙烯酰胺水凝胶注射隆乳后感染菌群研究[摘要]目的：了解聚丙烯酰胺水凝胶（Polyacrylamide Hydrogel，PAHG）注射隆乳术后并发感染的常见致病菌及部分抗生素耐药率。方法：对收治的42例PAHG注射隆乳术后并发感染的患者行无菌穿刺，并对穿刺物做细菌培养及药敏试验，对其细菌学特点、药物耐药性进行总结分析。结果：共检出病原菌116株,其中革兰氏阳性球菌86 株，占74.1%；革兰氏阴性杆菌25 株,占21.6%；真菌5 株，占4.3%。革兰氏阳性球菌对万古霉素、替考拉宁、喹奴普汀-达福普汀、头孢噻肟等抗生素的耐药率较低。革兰氏阴性杆菌对亚胺培南和阿米卡星的耐药率较低。结论：PAHG隆乳术后感染的主要致病菌是条件致病菌，其细菌学特点和对抗生素的耐药率对临床选用抗生素具有参考价值。 [关键词]聚丙烯酰胺水凝胶；感染；菌群；耐药性 [中图分类号]R655.8 [文献标识码]A [文章编号]1008-6455（2009）03-0290-03 Flora analysis of infection after Polyacrylamide Hydrogel Injection for augmentation mammaplasty CHEN Nian,LI Ming,DENG Ying,XIE Hai-tao,XIE Hong-ju (Department of Plastic and Reconstructive Surgery,The First Affiliated Hospital, University of South China, Hengyang 421001,Hunan,China) Abstract: Objective To investigate the pathogenic bacterium and drug resistance of pathogenic bacterium which infected after Polyacrylamide Hydrogel(PAHG) injection for augmentation mammaplasty. Methods In order to summarise and analyz the bacteriology characteristic and drug resistance, 42 patients who had infected after the PAHG were accepted Asepsis nyxised respectively.Then the aspirate was cultured and recived susceptibility test. Results There were 116 strains together. Among them, 86 strains were gram-positive coccobacteria (74.1%) and 25 strains were gram -negative bacilli (21.6% ),5 strains (4.3%) were eumycete. In the susceptibility test,we can find that the gram-positive coccobacteria was low to Vancomycin, Teicoplanin, Dalfopristin and Cefotaxime as well as the gram-negative bacilli was low to Imipenem and amikacin. Conclusions In the postoperative infection of PAHG,the chief pathogenic bacteria was opportunistic pathogen,and their bacteriological characters and the drug resistant rate to antibiotics may refer to the clinical choices of antibiotics. Key words: polyacrylamide hydrogel(PAHG); infection; microbial population; drug resistance 在我国，聚丙烯酰胺水凝胶作为医用软组织充填材料主要用于乳房整形已有十余年。因其组织相容性好，使用方便，手感好，曾经一度被认为是优良的隆乳填充材料，在美容整形临床中广泛运用。近年来国内