脉冲式及连续式CO2激光治疗汗管瘤疗效观察.docVIP

脉冲式及连续式CO2激光治疗汗管瘤疗效观察(1.上海医科大学华山医院皮肤科　上海200040　2.上海市南市区肿瘤防治院) 王月华　女,上海第一医学院医疗系毕业,上海市华山医院皮肤科副主任医师、副教授,中华医学会美学美容学上海市分会委员。发表论文20余篇,获”上海市科技进步三等奖”等奖项三项。[摘　要]　目的:寻找治疗汗管瘤的有效方法,减少或避免治疗反应及并发症。　方法:以CO2激光脉冲式与连续式两种方法治疗汗管瘤患者66人,皮损730灶,对照研究其治疗反应、疗效、并发症及发生的原因,并作统计学处理。　结果:治疗反应为创面较原皮损扩大,脉冲组发生率16.21%,连续组发生率79.94%,具非常显著的差异。一次治愈率均为97%以上。并发症的发生率脉冲组也低于连续组,具显著差异。　结论:〖HT5”K〗脉冲式CO2激光治疗汗管瘤对周围正常组织的热损伤、创面扩大的治疗反应和并发症少于连续式。 [关键词]　汗管瘤　脉冲激光　治疗反应 [中图分类号]R454.2　[文献标识码]A　[文章编号]1008-6455(2000)05-0344-02 CLINICAL STUDY ON COMPARATIVE TREATMENT OF SYRINGOMA WITH PULSED AND CONTINUOUS CO2　LASER WANG Yue-hua　ZHU Yi-ping Department of Dermatology,Hua shan Hospital,Shanghai Medical University(Shanghai　200040) [Abstract]　Objective:To find an effective therapy to treat for syringoma with less or no therapeutic reaction and no complications.　Methods:〖WT5”BZ〗66 patients with syringoma,about 730 focuses,underwent treatment with pulsed and continuons CO2 laser.The therapeutic reaction,effectiveness and complication were compared and analyzed statistically.　Results:The therapeutic reaction defined as that the lesion area enlarged after treatment.The occurrence rate in pulsed CO2 laser group was 16.21%,while in continuous CO2 laser group was 79.94%.The difference was significant.The cure rate was 97% in both groups.The occurrence rate of complication was lower in pulsed group than that in continuous group.The difference was significant.　Conclusion:The pulsed CO2 laser had a good cosmetic effect in the treatment of syringoma since it did less heat injury to surrounding area,and the occurrence rate of therapeutic reaction and complication was lower. [Key words]　Syringoma　Pulsed laser　Therapeutic reaction 汗管瘤是一种好发于女性面部的良性浅表性汗腺肿瘤,寻找本病合适有效的疗法已为临床皮肤科医生及有关人士所关注。?现将我们在1996年～1998年期间以脉冲式与连续式CO2激光对照治疗汗管瘤的临床研究结果报告如下。 1　临床资料 1.1　对象与病情　汗管瘤患者66人,均来自本科门诊,女63人,男3人。年龄18～52岁,平均35.3岁,30～40岁者占56.1%。皮损表现为1～3mm肤色或浅棕色扁平或半球形丘疹,孤立或群集分布于眼周、口周及颈、胸部。皮损典型者29人,非典型者37人,均经环钻术获得组织病理证实。以一个丘疹为一病灶,随机用脉冲或连续式CO2激光进