the peroxisomal 3-keto-acyl-coa thiolase b gene expression is under the dual control of pparα and hnf4α in the liver的过氧化物酶病3-keto-acyl-coa硫解酶b基因表达的双重控制下pparα和hnf4α肝脏.pdfVIP

Hindawi Publishing Corporation PPAR Research Volume 2010, Article ID 352957, 17 pages doi:10.1155/2010/352957 Research Article The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver 1, 2 1, 2, 3 4 ´ 1, 2 1, 2, 5 J. Chamouton, F. Hansmannel, J. A. Bonzo, M. C. Clemencet, G. Chevillard, M. Battle,6 P. Martin,7 T. Pineau,7 S. Duncan,6 F. J. Gonzalez,4 N. Latruffe,1, 2 S. Mandard,1, 2 ` 1, 2 and V. Nicolas-Frances 1 Centre de Recherche, INSERM U866, LBMN 6, Boulevard Gabriel, 21000 Dijon, France 2 Laboratoire de Biochimie M´etabolique et Nutritionnelle (LBMN), Facult´e des Sciences Gabriel, Universit´e de Bourgogne, 21000 Dijon, France 3 ´ INSERM U744, Laboratoire d’Epid´emiologie et Sant´e Publique, Institut Pasteur de Lille, 1 Rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France 4 Laboratory of Metabolism, Division of Basic Sciences, National Cancer Institute, Bethesda, MD 20892, USA 5 Lady Davis Institute for Medical Research, McGill University, 3755 Cˆote Ste. Catherine Road, Montreal, QC, Canada H3T 1E2 6 Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226-0509, USA 7 Laboratoire de Pharmacologie et Toxicologie, UR66, INRA, 31931, Toulouse, France Correspondence should be addressed to S. Mandard, stephane.mandard@u-bourgogne.fr Received 24 June 2010; Revised 1 December 2010; Accepted 9 December 2010 Academic Editor: Sander Kersten Copyright © 2010 J. Chamouton et al. This