383 cases of vaginal Candida infections flora identification and susceptibility Analysis（383例阴道念珠菌感染菌群鉴定和敏感性分析）.docVIP

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2017-09-05 发布于浙江
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383 cases of vaginal Candida infections flora identification and susceptibility Analysis（383例阴道念珠菌感染菌群鉴定和敏感性分析）.doc

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383 cases of vaginal Candida infections flora identification and susceptibility Analysis（383例阴道念珠菌感染菌群鉴定和敏感性分析）

383 cases of vaginal Candida infections flora identification and susceptibility Analysis To write papers network: [Keywords:] Candida vaginitis, strain identification, and drug sensitivity test [Abstract] Objective To analyze the characteristics of clinical isolates of Candida vaginitis, and anti-Candida drug resistance. The M27A program recommended by the method according to NCCLS (broth microdilution method detection fluconazole antifungal agents 52 deep pathogenic Candida clinical isolates in vitro antifungal activity of 383 specimens, mostly Candida albicans (9609%), followed by C. glabrata (261%), less tropical rosary bacteria (104%) and C. krusei (026%), drug sensitivity test: sensitivity of nystatin, amphotericin B in more than 90% resistance rate to itraconazole was highest (358% ), followed by fluconazole (175%). conclusions of clinical isolates of Candida vaginitis, there are smooth In addition to Candida albicans, Candida, Candida tropicalis and krusei Candida and other bacteria, nystatin and the sensitivity of amphotericin B against Candida, while the the itraconazole azole and fluconazole resistance rate is relatively high, should attract the attention of clinicians. [Keywords: candida vaginitis, strain identification, drug susceptibility testing [Abstract] Objective To analyze the clinic separable characteristics and compare the activities of fluconazole with other 5 antifungal agents in 383 cases of Candida viginitis. Methods Microbial population was determined by the method guided to the standard M27A recommended by the National Committee for Clinical Laboratory Standards . Results Ranked from the highest to to the lowest as C.albicans (9609%), C.glabrata (261%), C.troptical (104%), C.krusei (026%). Candistatin and amphotericin B were most effective against all the tested clinical Candida isolates (gt; 90%). The rates of drug fast were itraconazole (35.8%), fluconazole (175%). Conclusion C.albicans, C.glabrata, C.troptical, and C.krusei