MR医学影像文献Lin-2016-Localized One-Dimensional Single Voxe.pdfVIP

SPECTROSCOPIC METHODOLOGY - Note Magnetic Resonance in Medicine 76:1661–1667 (2016) Localized One-Dimensional Single Voxel Magnetic Resonance Spectroscopy without J Coupling Modulations 1 1 1 2,3 1 Yanqin Lin, * Liangjie Lin, Zhiliang Wei, Jianhui Zhong, and Zhong Chen Purpose: To acquire single voxel localized one-dimensional 1H diseases (1–3). Point resolved spectroscopy (PRESS) (4) magnetic resonance spectroscopy (MRS) without J coupling and stimulated echo acquisition mode (STEAM) (5) tech- modulations, free from amplitude and phase distortions. niques have been extensively used to acquire localized Methods: A pulse sequence, named PRESSIR, is developed for 1H MRS (6). However, both PRESS and STEAM sequen- volume localized MRS without J modulations at arbitrary echo time ces, especially when they are performed with long echo (TE). The J coupling evolution is suppressed by the J-refocused times (TEs), suffer from J modulations during TEs. For module that uses a 90 pulse at the midpoint of a double spin echo. scalar-coupled spins (such as lactate, glutamate, g- Results: The localization performance of the PRESSIR aminobutyric acid), J modulations can cause amplitude sequence was tested with a two-compartment phantom. The and phase distortions and lead to mutual cancellation proposed sequence shows similar voxel localization accuracy and, therefore, reduce informatio