心脏临时起搏术.ppt

[ALL] Coronary remodeling is an adaptive process by which the arterial wall changes in shape to maintain flow, despite the encroachment of plaque. This process may explain why less severe luminal narrowing may still be associated with progressive atherosclerosis and CAD. As plaque accumulates, the arterial wall reacts by remodeling. As atherosclerosis progresses toward the more severe stages pictured on the right, the lumen remains relatively constant because of compensatory expansion of the arterial wall. Eventually, in more severe stages of the disease, the artery is unable to expand further and the lumen begins to narrow. The same process may work in reverse with disease regression. That is, plaque can be removed from the arterial wall with little change in lumen size. Therefore, luminal measurement by quantitative coronary angiography (QCA) may be a less sensitive marker for the progression or regression of disease, in comparison to direct evaluation of plaque thickness through the use of intravascular ultrasound. [ALL] Coronary remodeling is an adaptive process by which the arterial wall changes in shape to maintain flow, despite the encroachment of plaque. This process may explain why less severe luminal narrowing may still be associated with progressive atherosclerosis and CAD. As plaque accumulates, the arterial wall reacts by remodeling. As atherosclerosis progresses toward the more severe stages pictured on the right, the lumen remains relatively constant because of compensatory expansion of the arterial wall. Eventually, in more severe stages of the disease, the artery is unable to expand further and the lumen begins to narrow. The same process may work in reverse with disease regression. That is, plaque can be removed from the arterial wall with little change in lumen size. Therefore, luminal measurement by quantitative coronary angiography (QCA) may be a less sensitive marker for the progression or regression of disease, in comparison to direct evalua