5-心血管-英-2015.ppt

Acute infective endocarditis: ABE a few days 1. Pyogenic bacteria: Staphylococcus aureus, group A hemolytic streptococci 2. trauma, wound infection?pyemia 3. Develop on normal valves：aortic, mitral 4. Morphology: Gross：ulceration, abscess : valvular destruction, vegetation: large, soft L/M：necrosis, lots of neutrophils, vegetation with plenty of bacteria Healing : vegetations fibrosis and scared 5. Clinical features: high fever, toxic appearance, rapid valvular destruction, and septic shock 6. Complications: Valvular penetrate, disrup