乌鲁木齐市水磨沟区婴幼儿口腔念珠菌病情况调查及危险因素分析.docVIP

精品论文 参考文献 乌鲁木齐市水磨沟区婴幼儿口腔念珠菌病情况调查及危险因素分析 （新疆医科大学第二附属医院 新疆 乌鲁木齐 830028） 【摘 要】目的：了解乌鲁木齐市水磨沟区婴幼儿口腔念珠菌患病率及其危险因素。方法：组织0-3岁婴幼儿体检，进行口腔初步检查并对有口腔白色斑块状病变的患儿进行进一步确诊检测，以问卷形式调查患儿和对照婴幼儿一般情况，并定性检测肝炎、HIV病毒，分析口腔念珠菌病发病的危险因素。结果：在体检的1258例婴幼儿中，口腔初检出有口腔白色斑块表现的患儿180例，经实验室进一步检测，均确诊为口腔念珠菌感染患儿，患病率为16.52%。经Logistic回归分析，患儿与非患儿之间在营养状态、母亲乳头卫生、母亲患真菌感染病、婴幼儿长期服药史及罹患其它疾病等因素方面，存在差异，plt;0.05，其余因素方面则无统计学差异。结论：乌鲁木齐市水磨沟区婴幼儿口腔念珠菌病患病率较高，患儿营养状态、母亲乳头卫生、母亲患真菌感染病、婴幼儿长期服药史及罹患其它疾病为该病的易感因素，患儿家长及公众应从以上几个方面做健康宣传教育。 【关键词】婴幼儿；口腔念珠菌感染；危险因素 【中图分类号】R781 【文献标识码】A 【文章编号】1004-6194（2015）02-0208-02 【Abstract】Objective: To understand the morbidity of oral candidiasis and its risk factors in ShuiMoGou of Urumqi. Methods: We organize the infants and young children from 0 to 3 years old to have physical examinations. Then we perform oral initial checkups on them and make children with oral white patches get further confirmed detection. The general conditions of infants and control infants are checked in the form of questionnaire and the hepatitis and virus of HIV are also checked qualitatively. Finally, the risk factors of oral candidiasis will be analyzed. Results: Among 1258 infants and young children who have had the physical , there are 180 cases with the oral white patches through preliminary examination. All of them are diagnosed with oral candidiasisthrough further testing in the lab. The morbidity is 16.52%. In the analysis of Logistic regression, there exist differences between children with oral candidiasis and children without oral candidiasis, such as nutritional status , mothers nipple hygiene, mother suffering from fungal infections disease,drugta king history and other diseases . p lt; 0.05.There are not significant differences in other factors.Conclusion: The morbidity of infant oral candidiasis is higher in ShuiMoGou of Urumqi. The nutritional status in infants, mothers nipple hygiene, fungal infections, drug-taking history and other diseases are the predisposing factors for the disease