病理学经典图片集(胰腺).pptVIP

病理学经典图片集;;Chronic Pancreatitis ;Chronic pancreatitis is characterized by patchy fibrous replacement of whole lobules or parts of lobules, focal fat necrosis in different stages, and chronic inflammation.? Grossly, depending on the degree of injury, the gland may have a normal outline, lobular pattern, and color but be slightly firm, or it may be smaller than normal, bosselated, rock-hard, and display foci of fat necrosis, calcification, or fully developed calculi.;Gross:? This chronically inflamed pancreas is small and scarred.? The dilated pancreatic duct contains a stone (arrow).;Plain film of abdomen:? This is an example of chronic pancreatitis with marked calcification of the pancreatic parenchyma. ;The fibrous scarring of the pancreas is highlighted with the Trichrome stain. The fibrous septa appear as blue bands surrounding the residual pancreatic lobules, which stain red.;Shows the dense interstitial fibrosis surrounding two pancreatic lobules. Note there is also an increase in intralobular fibrous tissue and there is chronic inflammation.;The exocrine portion of the gland is most severely affected. There is almost total atrophy and fibrous replacement of pancreatic acini with relative preservation of the pancreatic ducts and islets of Langerhans (arrows). The intralobular pancreatic ducts are irregularly shaped and are embedded in chronically inflamed fibrous tissue. Several preserved islets are marked with arrows.;Adenocarcinoma of the Pancreas ;Gross: These are sections taken through a carcinoma of the head of the pancreas. The lesion is an ill-defined, tan-white mass which largely effaces the normal lobular architecture of the pancreas. The tumor blends imperceptibly into the surrounding pancreas and invades the wall of the duodenum.? Two lymph nodes contain metastatic carcinoma. It may be virtually impossible for the surgeon in the operating room to distinguish carcinoma of the pancreas from chronic pancreatitis.;Is a low power view of the glass sl