维生素E联合天晴甘平治疗非酒精性脂肪性肝病临床疗效观察.docVIP

精品论文 参考文献 维生素E联合天晴甘平治疗非酒精性脂肪性肝病临床疗效观察 刘雅静 　　北京市昌平区医院　北京　１０２２００ 作者简介:刘雅静,硕士,主治医师 　　【摘要】　目的　探讨维生素E联合天晴甘平治疗非酒精性脂肪性肝病的疗效.方法　选择２０１３年９月至２０１４年９月期间我院收治的非酒精脂肪性肝病患者５９例,将其随机分为对照组２９例、治疗组３０例,对照组在常规治疗基础上加用维生素E,治疗组在对照组基础上加用天晴甘平,两组均连续治疗２４周, 比较两组临床疗效、患者肝功能指标以及血脂变化情况.结果　治疗组治疗总有效率为９３．３３％,对照组治疗总有效率为７２．４１％,两组比较,差异具有统计学意义(P＜０．０５);治疗前两组患者各肝功能指标差异不具有统计学意义(P＞０．０５),治疗后两组患者各肝功能指标均较治疗前显著改善(P＜０．０５),且治疗组改善情况优于对照组(P＜０．０５);治疗前两组患者血脂水平不存在统计学差异(P＞０．０５),治疗后治疗组TG水平显著下降(P＜０．０５),而对照组治疗前后血脂水平无差异(P ＞０．０５).结论　维生素E联合天晴甘平治疗非酒精性肝病能够有效提高临床疗效,改善患者肝功能以及部分血脂水平,且用药较安全可靠,值得临床推广运用. 【关键词】　天晴甘平;　维生素E;　非酒精性脂肪性肝病ObservationoncurativeeffectofVitamineEcombinedwithTianqingganpingintreatmentofNon－alcoholicFattyLiverDisease(NAFLD)．　Liuyajing　(CangpingdisitrictHospital,Beijing,１０２２００)【Abstract】ObjectiveToinvestigatethecurativeeffectofVitamineEcombinedwithTianqingganpingintreatmentofnon－alcoholicfattyliverdiseases．MethＧods５９patientswithnon－alcoholicfattyliverdiseasesinseptember２０１３~september２０１４inourhospitalpatients,randomlydividedthemintocontrolgroup２９cases,treatmentgroup３０cases,controlgroupintheconventionaltreatmentcombinedwithVitamineE,thetreatmentgroupinthecontrolgroupbasedontheuseofTianqingganping,thetwogroupsweretreatedfor２４weeks,comparisontheclinicaleffectofthetwogroups,liverfunctionindicesinpatientswithbloodlipidchanges．ResultsInthetreatmentgroup,thetotaleffectiveratewas９３．３３％,thecontrolgrouptotaleffectiveratewas７２．４１％,twogroups,withstatisticallysignifiＧcantdifference(P＜０．０５);thedifferenceofthehepaticfunctionindexesbeforetreatment,patientsinthetwogroupswasnotstatisticallysignificant(P＞０．０５)．AfＧterthetreatmentofthehepaticfunctionindexofthetwogroupsofpatientsweresignificantlyimproved(P＜０．０５),andthetreatmentgrouptoimprovethesituaＧtionbetterthanthecontrolgroup(P＜０．０５);bloodlipidlevelsinthetwogroupsbeforetreatmentwasnotsignificantdifference(P＞０．０５),bloodlipidlevelsaftertreatmentintreatmentgroupdecreasedsignificantly(P＜０．０５),whilethecontrolgrouphadnodifferenceinlipidlevelsbeforeandaftertreatment(P＞０．０５)．ConＧclusionsVitamine