美托洛尔与贝那普利联合治疗陈旧性心梗合并心力衰竭的临床疗效观察.docVIP

精品论文 参考文献 美托洛尔与贝那普利联合治疗陈旧性心梗合并心力衰竭的临床疗效观察 1江苏省苏州市吴中人民医院门诊部； 2 江苏省苏州市吴中人民医院急诊科；3 江苏省苏州市吴中人民医院心内科 215128 摘要：目的：分析研究美托洛尔与贝那普利联合治疗陈旧性心梗合并心力衰竭的临床疗效。方法：随机选取2012年5月-2014年5月本院接诊的70例陈旧性心梗合并心力衰竭患者作为研究对象，并将其依据临床用药的不同随机分为对照组以及观察组，每组各35例；其中对照组患者采用利尿剂、强心剂等常规药物进行治疗并在此基础上加用贝那普利，观察组患者则在对照组的治疗基础上加用美托洛尔。比较两组治疗前后6min内步行距离以及临床症状、心功能检测结果以及治疗有效率、不良反应发生几率等。结果：观察组患者的治疗总有效率明显高于对照组，上述数据经统计学处理后显示P＜0.05，故具有统计学意义。两组患者对比不良反应发生几率未见明显差异（P＞0.05）。经治疗后观察组患者的6min步行距离、射血分数、左室舒张早期血流传播速度以及左室舒张末内径等指标均明显优于治疗前以及对照组，两组组间以及两组组内对比结果经统计学处理后均显示P＜0.05，故具有统计学意义；相较于治疗前对照组上述指标也有较大改善（P＜0.05）。结论：采用美托洛尔与贝那普利联合治疗陈旧性心梗合并心力衰竭临床效果显著，且心功能改善程度更为明显、不良反应发生几率较低。 关键词：陈旧性心梗；心力衰竭；美托洛尔；贝那普利 Clinical efficacy of metoprolol and benazepril combination therapy with old myocardial infarction with heart failure CHEN xiao-dan，LUO Ming-Xiong，YANG Ling （Department of Cardiology，Wuzhong peoples hospital，Suzhou 215128，Jiangsu，China） Abstract Objective：To analyze the study of metoprolol and benazepril combination therapy with old myocardial infarction with heart failure clinical efficacy.Methods：Randomly selected in May 2012 -2014 May 70 cases of hospital admissions for heart failure in patients with old myocardial infarction as the research object，and according to different randomized clinical medicine into the observation group and control group，each each group of 35 cases；in which the control group were treated with diuretics，cardiac and other conventional drugs for treatment and on this basis，plus benazepril，observe patients in the control group，treatment based on the use of metoprolol.Comparison of the two groups before and after treatment within 6min walking distance as well as the clinical symptoms，heart function test results and treatment efficiency，such as the probability of adverse events.Results：The total efficiency of the treatment of patients was significantly higher after the above data show statistically P lt;0.05，it is statistically significant.Comparing two groups of patients with adverse events was no significant difference