臭氧联合阿德福韦脂胶囊治疗乙肝四年随访总结.docVIP

精品论文 参考文献 臭氧联合阿德福韦脂胶囊治疗乙肝四年随访总结 安良敏 赖连娣 吴雪玲 　　(英德市人民医院 广东清远 513000) 　　【摘要】目的:总结臭氧联合阿德福韦脂胶囊治疗乙肝四年随访情况。方法：采取回顾性方法对我院2010年1月-2013年12月来就诊治疗、符合观察标准的乙肝患者112例，均采取臭氧联合阿德福韦脂胶囊治疗，并对4年来的治疗随访情况进行总结与分析。结果：患者随访后1-4年的ALT、TBil、ALB和Child-pugh评分较治疗前有明显的改善，且各组数据比较有统计学意义(P＜0.05)。随访1-4年患者的HA、PCⅢ和CⅣ较患者治疗前有明显的改善，且数据的比较差异有统计学意义(P＜0.05)。随访1年后112例生存，生存率100.0%；随访2年后110例生存，生存率98.2%；随访3年后109例生存，生存率97.3%；随访4年后107例生存，生存率95.5%。治疗后4年的随访观察，共有11例出现病情反弹，反弹率为9.8%。5例患者转化为肝硬化，3例患者转化为肝癌。本组患者治疗中未见有任何的不良反应发生。结论：临床中对于乙肝患者采取臭氧联合阿德福韦脂胶囊治疗效果明显，远期效果也较好，改善患者预后，有效的降低病情恶化，提高患者生活质量。 　　【关键词】 乙肝 臭氧 阿德福韦脂胶囊 随访观察 　　【中图分类号】R969 【文献标识码】A 【文章编号】2095-1752（2014）17-0071-03 　　The Ozone combine Adefovir Dipivoxil Capsules treatment of hepatitis B lipid capsule summary of four years of follow-up 　　An Liangmin,Lai Liandi,Wu Xueling 　　(Department of infectious diseases,Peoplersquo;s Hospital of Yingde City,Guangdong Qingyuan 513000) 　　【Abstract】Objective: To summarize the Ozone combine Adefovir Dipivoxil Capsules treatment of hepatitis b 4 years follow-up. Methods:Retrospective methods in our hospital in January 2010 - December 2013 to clinic treat -ment, accord with standard of observation of 112 cases of patients with chronic hepatitis b, the Ozone is adopted combine Adefovir Dipivoxil Capsules treatment, and treatment for four years follow-up summary and analysis. Result:Before and after the patients were followed for 1-4 years, ALT, TBil, ALB and Child-pugh score improved significantly compared with the treatment, and each set of data was statistically significant (P lt;0.05). 1-4 years follow-up in patients with HA, PC Ⅲ and C Ⅳ patients before treatment had obvious improvement, and data com -parison difference was statistically significant (P lt; 0.05). Follow-up of 1 year after 112 cases of survival, the survival rate was 100.0%; 110 cases were followed up for 2 years survival, survival rate was 98.2%; 109 cases were followed up for 3 years survival, survival