血液透析患者血清肿瘤标志物的检测及意义.docVIP

精品论文 参考文献 血液透析患者血清肿瘤标志物的检测及意义 赣州市人民医院 江西 赣州 341000 2.宁都县人民医院 江西 宁都 342800 摘要：目的 研究分析血液透析患者血清肿瘤标志物的检测及临床意义。方法 选取我院收治的100例血液透析的患者为观察组，择期选其未行血透的尿毒症患者100例为对照组，选择100例健康者为标准组。结果 对照组与观察组相比，Ferritin检测具有显著性差异（P＜0.05），具有统计学意义;其它各个肿瘤标志物水平间无显著性差异（P＞0.05）,无统计学意义；三组综合相比，Ferritin、CA125以及CA19-9检测水平间具有显著性差异（P＜0.05），其它肿瘤标志物无显著性差异（P＞0.05）。结论 血液透析的患者肿瘤标志物Ferritin、CA125以及CA19-9水平具有不同程度的升高，但血透不能有效的对肿瘤标志物进行清除。 关键词：血液透析；肿瘤标志物；检测；临床意义 【中图分类号】R856.2【文献标识码】A【文章编号】1001-5213(2016)08-0245-01 Detection and significance of serum tumor markers in patients receiving hemodialysis Tan Fei 1 Hu Zhihuan 2 (corresponding author) 1.Ganzhou Peoples Hospital Ganzhou Jiangxi 341000 2.Dinin county Peoples Hospital Ningdu Jiangxi 342800 Abstract: objective to study the analysis of serum tumor markers in patients receiving hemodialysis detection and clinical significance. Methods select 100 cases of hemodialysis patients of our hospital for observation group, the quiet choose its no hemodialysis uremic patients 100 cases as control group, 100 cases of healthy subjects as the standard group. Results compared to control group and observation group, Ferritin detection has significant difference (P lt; 0.05), statistically significant; There was no significant difference between each other tumor markers level (P gt; 0.05), no statistical significance; Compared three groups of comprehensive, Ferritin, CA125 and CA19-9 levels between has significant difference (P lt; 0.05), and other tumor markers there was no significant difference (P gt; 0.05). Conclusion hemodialysis patients with tumor markers Ferritin, CA125 and CA19-9 levels with different degree of increase, but the hemodialysis cannot be effective to remove tumor markers. Key words: hemodialysis; Tumor markers; Detection; Clinical significance 肿瘤标志物是因肿瘤细胞及组织产生的异常生物活性物质，目前肿瘤标志物的检测技术主要是针对肿瘤的相关抗原，该相关抗原并不是肿瘤细胞特有的，而是肿瘤相关抗原所表达的量。近几年在临床中常采用几种标志物联合检测来增加肿瘤诊断的阳性率。本文选我院收治的血液透析患者，未行血透的尿毒症患者以及健康者各100例为研究对象，对血液透析患者血清肿瘤标志物的检测及临床意义进行研究分析。 1