血糖浓度对心脑生理性摄取的影响.docVIP

精品论文 参考文献 血糖浓度对心脑生理性摄取的影响 DOI：10.7504/nk2016010203 中图分类号：692 文献标识码：A 　　摘要：目的 探讨血糖浓度对PET/CT检查中心脑生理性摄取影响的临床应用价值。方法 回顾性分析2012年12月至2014年2月在行PET/CT检查的患者或体检者，排除患有心脏及脑部恶性肿瘤、严重心功能不全及弥漫性脑梗等疾病，影响心肌及脑组织正常摄取者。入选共225名检测者，以血糖浓度不同分三组：血糖正常组、血糖稍高组、血糖较高组。分别观察各组心脏与脑组织的PET图像，并对其SUVmax值进行测量，根据图像质量及摄取程度分为0~3四个等级，最后进行两两组间对比。结果 血糖较高组心肌的各个级别的比例与其它两组比较Plt;0.05，具有统计学意义。随着血糖水平的降低，心肌显影比例升高。血糖正常组心肌显影2级、3级的比例明显高于其他两组。而脑组织对18F-FDG的摄取值与血糖值呈反比，血糖正常组gt;血糖偏高组gt;血糖较高组，且与其他两组比较Plt;0.05，具有统计学意义。结论 空腹血糖浓度对人体心肌或脑组织的显像或生理性摄取SUVmax产生了一定影响，了解这些生理性摄取显像规律变化，认真做好 l8F-FDG PET/CT检查前的准备，可为核医学影像医师阅片提供更为详尽信息，保证了图像质量，有利于提高临床诊断的准确性。 　　关键词：血糖 生理性摄取 最大标准摄取值 阈值 肿瘤 　　The influence of blood glucose concentration of cardio-cerebral physiological uptake 　　ZHANG Yun，LIU Chun-hai， FENG Xiao-wei， LI Rei-min，CHEN Yong-jie，DU Wen-xia 　　【Abstract】 Objective To explore the clinical application of blood glucose concentration effect on cardio-cerebral physiological uptake value. Methods Retrospective analysis from December 2012 to February 2014 in hospital，Line PET / CT in patients or subjects were examined，Exclusion criteria: Suffering from heart and brain tumor， severe cardiac insufficiency and diffuse diseases such as cerebral infarction， myocardial and brain normal intake is not recorded in the group.The study of 225 cases， to the level of fasting blood glucose divided into three groups: Normal blood glucose group、Higher blood glucose group、High glucose group. Observed and measured the heart and brain physiology of 18F-FDG uptake in the image and SUVmax values were compared. Results In the fasting blood glucose level under different myocardial imaging， all levels of higher concentration ratio of the group with other two groups P lt;0.05， statistically significant.With the decrease in blood glucose levels， increased the proportion of cardiac development， normal cardiac development Level 2， Level 3 percentage significantly higher than the other two groups; The brain uptake values and the blood glucose level is inv