细菌黑色素的合成途径及生物功能研究进展-微生物所期刊联合编辑部.PDFVIP

微生物学通报 Feb. 20, 2014, 41(2): 334343 Microbiology China © 2014 by Institute of Microbiology, CAS tongbao@ DOI: 10.13344/j.microbiol.china.130524 专论与综述 细菌黑色素的合成途径及生物功能研究进展 柴保中 王禾 彭珍荣 沈萍 陈向东* ( 430072) 摘 要黑色素的合成是生物界从细菌到人类都普遍存在的现象。黑色素在生物体中具有抗紫 外辐射、清除自由基等功能,对于生物的生长发育虽非必需,却能极大提高生物体的生存竞争能 力。此外,黑色素合成途径中的关键酶类如酪氨酸酶能代谢不少酚类物质, 在化工等领域具有 实际应用价值。本文重点从细菌黑色素的种类、生物合成途径、黑色素的生物学功能方面进行 阐述。 关键词黑色素，细菌酪氨酸酶, HGA 途径, 生理功能 Advance in study on pathway of melanin biosynthesis and their physiological function in bacteria CHAI Bao-Zhong WANG He PENG Zhen-Rong SHENG Ping * CHEN Xiang-Dong (College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China) Abstract: Production of melanin has been described in a variety of life forms ranging from bacteria to human. Though melanin is not essential to the growth of organisms, it can help to improve their competitive abilities through confering organisms diverse functions such as resistance to UV radiation and toxic free radicals elimination. Nowadays, research on enzymes essential for the formation of melanin has attracted more attentions because they can metabolize dozens of phenol compounds. It made these enzymes, like tyrosinase, a significant value in biotechnology application. This review summarizes the present knowledge of melanin categories, biosynthetic pathways and physiological functions. Keywords: Melanin, Bacterial tyrosinase, HGA pathway, Physiological function (Melanin) [1]