“Functional” RNAs RNA catalysts, miRNA, sRNA, RNAi [课件].pptVIP

Functional RNAs;RNA catalysts, miRNA, sRNA, RNAi... Kevin Klein, PhD. Pathobiology 551 Monday 10/26/2009 RNAs have many functions rRNA (ribosomal RNA) tRNA (transfer RNA) mRNA (Messenger RNA) snRNA (including snoRNA) (Small nuclear RNA- splicing) Other ribozymes Telomerase RNA (telomerase maintenance) siRNA (small interfering RNA – RNA silencing) shRNA (short hairpin – RNA silencing) Pri-miRNA; miRNA ( (primary) micro RNA - regulation) sRNA (small RNA – bacteria) gRNA (guide RNA – RNA editing) Genomic RNA (viruses) “Regulatory” RNAs in prokaryotes Can Regulate at the level of... mRNA produc