Introduction(PartII)清华大学生物化学实验（英文版）.pptVIP

Part II Bioenergetics and Metabolism What is metabolism The entire set of enzyme-catalyzed transformations of organic molecules in living cells The sum of catabolism and anabolism Provides fascinating and revealing insights into life, with countless applications in medicine, agriculture and biotechnology Functions of metabolism Obtain chemical energy from sunlight or nutrients Convert nutrient molecules into the cell’s own characteristic molecules Polymerize monomeric precursors into macromolecules Synthesize and degrade biomolecules required for specialized cellular functions Cycling of CO2 and O2 in the atmosphere Producers Consumers Cycling of nitrogen in the atmosphere (NH4+) (NO2-, NO3-) Energy relationships between catabolic and anabolic pathways Three types of nonlinear metabolic pathways Course outline Principles of bioenergetics (Ch13) Major catabolic pathways (Ch14-18) Oxidative phosphorylation and photophosphorylation (Ch19) Major anabolic pathways (Ch20-22) Integration and hormonal regulation of metabolism (Ch23) Course Calendar WEEK DATE CONTENTS 1 Sept. 14 Introduction to the course Ch. 13---Principles of Bioenergetics 2 Sept. 21 Ch. 14--Glycolysis and the catabolism of hexoses 3 Sept. 28 Ch. 16---The citric acid cycle 4 Oct. 5 National Day Holiday 5 Oct. 12 Ch. 17---Fatty acid catabolism Ch. 18---Amino acid oxidation and the production of urea 6 Oct. 19 Ch. 19, Part I---Oxidative phosphorylation 7 Oct. 26 Ch. 19, Part II---Photophosphorylation Summary of Catabolism 8 Nov. 2 Ch. 20---Carbohydrate biosynthesis 9 Nov. 9 Ch. 21---Lipid biosynthesis 10 Nov. 16 Ch. 22---Biosynthesis of amino acids, nucleotides and related molecules 11 Nov. 23 Ch. 23--- Hormonal regulation and integration of mammalian metabolism Summary of Biosynthesis 12 Nov. 30 Ch. 24---Genes and chromosome 13 Dec. 7 Ch. 25---DNA metabolism 14 Dec. 14 Ch. 26---RNA metabolism 15 Dec. 21 Ch. 27---Protein meta