呼吸科呼吸系统4 课件.ppt

Central Alveolar Hypoventilation (Ondine’s Curse) Central alveolar hypoventilation is a rare disease in individuals who are born without ventilatory chemosensitivity Breathing adequate when awake, but not when asleep or during sleeping No response to hypercapnia and hypoxia 阿尔茨海默症防治相关知识埃及的金字塔有建造方法动画艾司洛尔在神经外科重症中的应用二级二班防溺水等安全教育 阿尔茨海默症防治相关知识埃及的金字塔有建造方法动画艾司洛尔在神经外科重症中的应用二级二班防溺水等安全教育 阿尔茨海默症防治相关知识埃及的金字塔有建造方法动画艾司洛尔在神经外科重症中的应用二级二班防溺水等安全教育 阿尔茨海默症防治相关知识埃及的金字塔有建造方法动画艾司洛尔在神经外科重症中的应用二级二班防溺水等安全教育 5.4 Control of Respiration Breathing is a critical robust homeostatic process that ensures adequate levels of oxygen in blood and provides a means to remove carbon dioxide from the body Basic Requirements for Respiratory Regulation It must be automatic Maintenance of CO2 and O2 levels should not depend on levels of consciousness or alertness It must be adaptable to the needs of the organism There must be mechanisms to compensate for changes in oxygen uptake or CO2 production. It must be subject to voluntary control There must be mechanisms to voluntarily override the respiratory control mechanisms at least for brief periods of time Respiratory Centers and the Basic Respiratory Center Respiratory center Brain regions or the spinal cord that involve in the generation of rhythmic respiratory pattern and the regulation of respiratory movement; they are located in the spinal cord, brainstem, cortex, thalamus etc. Basic respiratory center Brain parts that are responsible for generation of basic respiration patterns It is located in the brainstem The Experiment Done by Lumsden in the Cat Conclusions Upper pons-pneumotaxic center; lower pons-apneustic center (not accepted); Spinal cord-Basic respiratory center; spinal cord: Cut at Breathing pattern (vagus nerve intact) Breathing pattern (vagus nerve cut off) Midbrain and the pons Nearly normal Deep and slow Mid pons Nearly normal Apneustic breathing Pons and medulla Irregular Cheyne-Stokes breathing Medulla and the spinal cord No