无创性脉波检测装置测量中心动脉压的准确性和重复性研....docVIP

无创性脉波检测装置测量中心动脉压的准确性和重复性研究 李维维1，陈良龙1，李卫华2 谢 强2 李金国1 罗育坤1 林朝贵1 彭亚飞1 郑行春1 黄峥嵘2 【摘要】 背景 中心动脉压（central aortic pressures，CAP）是升主动脉根部的血压。研究结果表明CAP与心脑血管病终点事件密切相关，如何准确、方便的测量CAP是目前研究的热点。 目的 评价无创性检测CAP的准确性和重复性。 方法 选择105例动脉粥样硬化患者（AS组）和83例非动脉粥样硬化患者（NAS组），采用无创性桡动脉脉波检测装置测量CAP、肱动脉收缩压（BSBP）和桡动脉增益指数（radial artery augment index，rAI），并与导管法直接压力测量结果做比较。 结果 无论AS组还是NAS组，无创法与导管法获得的CAP测值均具有高度的一致性及相关性。无创法CAP及rAI测值在测量者间及测量者内重复测量的一致性及可重复性均很高。无论AS组还是NAS组，CAP均低于对应的BSBP，但AS组CAP和BSBP的差值显著小于NAS组。结论 无创性脉波检测装置测量CAP和rAI的准确性高；虽然中心动脉压低于肱动脉压，但是动脉粥样硬化使此差别显著缩小。 【关键词】 中心动脉压； 无创性； 准确性； 重复性 Accuracy and reproducibility of measuring central aortic pressures non-invasively by radial arterial pulse wave testing equipment LI Weiwei1, CHEN Lianglong1*, Li weihua2. Department of cardiology, Union hospital affiliated to Fujian medical university, Fuzhou 350003, Fujian province China 【Abstract】 Background Central aortic pressures（CAP） is defined as the pressure of ascending aorta root. Previous studies demonstrated CAP closely related with end-point events of cardio-cerebrovascular diseases. How to measure CAP accurately and conveniently is a focus currently. Objectives To evaluate the accuracy and the reproducibility for measuring CAP non-invasively by radial arterial pulse wave testing equipment，and to explore the difference between CAP and brachial arterial systolic blood pressure（BSBP）atherosclerotic patients（AS） and 83 non-atherosclerotic patients（NAS）were recruited. CAP and rAI were determined non-invasively by radial artery pulse wave testing equipment and invasively by catheterization，respectively. Results There was a good agreement and linear relationship between CAPs derived non-invasively and invasively either in AS or NAS. The repeated CAP measurements respectively by two observers also revealed a good agreement and reproducibility in inter- or intra-observers. CAP was lower than BSBP either in AS or NAS, but the difference was diminished significantly in AS. Conclusions CAP m