酶的调控机制.pptVIP

Regulatory Strategies: Enzymes and Hemoglobin He jing Introduction The biological activity of proteins is regulated in four principal ways: 1. Allosteric control. 2. Multiple forms of enzymes. 3. Reversible covalent modification. 4. Proteolytic activation. 1. Allosteric control.Allosteric proteins contain distinct regulatory sites and multiple functional sites. Regulation by small signal molecules is a significant means of controlling the activity of many proteins. The binding of these regulatory molecules at sites distinct from the active site triggers conformational c