肺动脉高压流行病学与我国PAH资料分析.ppt

2011-2 ;In 1891, the German pathologist Romberg observed that the heart of an individual, suffering from a stricture of the pulmonary arteries due to severe sclerosis, was double the size of a man′s fist. He again named this disease sclerosis of the pulmonary arteries. ;1. 肺动脉高压 特发性肺动脉高压 遗传性 BMPR2 ALK1, endoglin 未知突变 药物或毒物 相关性 结缔组织病 心脏或大血管左向右分流 门脉高压 HIV 感染 血吸虫病 慢性溶血性贫血 1′肺静脉闭塞病，肺毛细血管瘤样病;流行病学;流行病学;原发性肺动脉高压 发病率: 1-2/百万人口 成人女男比 1.7:1