Charles River 大鼠模型供应.docx

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Charles River 大鼠模型供应

Charles River 大鼠模型供应Dahl/Salt Sensitive (Dahl/SS) RatSS/JrHsdMcwiCrlORIGINInbred from a congenic control group of Dahl/SS rats (SS/JrHsd) obtained from Dr. Theodore Kurtz (UCSF, CA) which were originally derived from the Harlan SS/Jr colony. Maintained at the Medical College of Wisconsin since 1991, this strain has undergone considerable marker-selected breeding to eliminate residual heterozygosity and genetic contamination. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested. (Cowley et al. 2000, Physiol. Genomics 2:107-115). To Charles River in 2001.STRAIN CODE 320COAT COLOR White (albino) RESEARCH APPLICATIONhypertension, diastolic heart failure, nephropathyNote: The SS-13BN is the normotensive control for the Dahl/SS rat.BREEDING LOCATIONUSADDITIONAL INFORMATIONFor more information about?Dahl/Salt Sensitive (Dahl/SS) rats, please contact us at info@./fr-FR/ProdServ/ByType/ResModOver/ResMod/Pages/DahlSSRat.aspxLong-Evans RatCrl:LEORIGINOriginated by Drs. Long and Evans in 1915 by crossing several Wistar Institute white females with a wild gray male. To Charles River from Canadian Breeding Farm and Laboratories in 1978.COAT COLORWhite with black hood; occasionally white with brown hoodRESEARCH APPLICATIONgeneral multipurpose model, behavioral research, diet-induced obesityBREEDING LOCATIONGermany, USADDITIONAL INFORMATIONFor more information about Long-Evans rats, please contact us at info@Goto-Kakizaki (GK) RatGK/TohiCskCrljCrlORIGINTheGoto-Kakizaki (GK) rat is a non-obese Wistarsubstrain which develops Type 2 diabetes mellitus early in life. The model was developed by Goto and Kakizaki at?Tohoku University, Sendai, Japan in 1975. To Chugai Pharmaceutical Co.To Charles River Japan in 1995.? To Charles River Laboratories in 2006.STRAIN CODE 460COAT COLOR White (albino) RESEARCH APPLICATIONnon-obese Type 2 diabetes, mild hyperglycemia, insulin resistant, hyperi

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