超声实时组织弹性成像在鉴别乳腺良恶性病变中应用价值.docVIP

超声实时组织弹性成像在鉴别乳腺良恶性病变中应用价值 　　【摘要】目的:探讨超声实时组织弹性成像（RTE）对乳腺良恶性病变的鉴别诊断价值。方法 对121例患者共140个乳腺病变，先常规采用二维及彩色多普勒超声检查，再行超声弹性成像检查，并采用5分法对其硬度进行评价。以术后病理诊断结果为标准，分别计算常规彩超检查与彩超联合弹性成像两种方法在判定乳腺恶性病变的准确性、敏感性和特异性。结果 常规彩超诊断乳腺恶性病变的准确性、敏感性和特异性分别为82.1%、79.3%、84.1%；彩超联合超声弹性成像诊断乳腺恶性病变的准确性、敏感性和特异性分别为96.4%、96.6%、96.3%。乳腺良性病变弹性成像平均分值为1.78±0.82，恶性病变平均分值4.31±0.58，二者差异有统计学意义(P＜0.01)。结论 超声实时组织弹性成像有助于乳腺疾病的良恶性鉴别。 　　【关键词】超声检查；实时组织弹性成像, 乳腺疾病 　　【中国分类号】 R5 R4【文献标识码】A【文章编号】1044-5511（2011）11-0361-02 　　 　　【Abstact】 Objective To evaluate the diagnostic value of Real-time Tissue Elastography (RTE) in differentiating benign and m alignant breast tumors. Methods One hundred and twenty-one patients with breast lumps (140 lesions) were B-mode imaging, Colour Doppler flowing imaging (CDFI) and Real-time Tissue Elastography. The elastogram was graded using 5-score evaluating method. The postoperative pathological diagnosis was used as gold standard, and the sensitivity, specificity and accuracy of RTE and two-dimensional ultrasonography combined with RTE in diagnosis of breast cancer were calculated. Result The accuracy, sensitivity, and the specificity of B-mode imaging and CDFI for differentiation were 82.1%、79.3%、84.1%. The accuracy, sensitivity, and the specificity of B-mode imaging , CDFI and RTE for differentiation were 96.4%、96.6%、96.3%. The average scroes of benign and m alignant leisions was 1.78±0.82 and 4.31±0.58.There was significant difference between them(P＜0.01). Conclusion Real-time Tissue Elastography is helpful in differentiating between m alignant and benign breast lesions. 　　【Key words】 Ultrasonography; Real-time Tissue Elastography, Breast diseases 　　 　　实时组织弹性成像（Real-time Tissue Elastography，RTE）是近年来发展的一种对组织力学特征成像的超声新技??，能够分辨不同硬度的物体，反映被测组织与周围组织相比较的硬度相对值。本文运用该技术对乳腺病变进行研究，以期探讨其在乳腺良恶性病变鉴别诊断中的应用价值。 　　1 资料与方法 　　1.1 研究对象:行手术治疗并均有病理结果的121例患者共140个乳腺肿块，其中女性116例，男性5例，年龄12-83岁，平均年龄48.0±9.6岁，肿块大小约3-60mm，平均大小约14.3±8.8mm。 　　1.2 仪器:采用HITACHI公司的EUB-7500超声诊断仪，线阵探头，频率5-13MHZ，配备有实时彩色超声弹性成像技术。 　　1.3 检查方法