几种中孕引产方式比较.docVIP

几种中孕引产方式比较 　　[摘要] 目的 探讨改进中孕引产的方法。 方法 选择孕15～27周、有引产指征而无引产禁忌的要求引产者，随机分为A组（米非司酮+利凡诺）、B组（已烯雌酚+利凡诺）和C组（利凡诺）。观察三组引产成功率、产程启动时间、总产程、产时及产后2 h出血量及安全性。 结果 A组与B组引产成功率高于C组（P＜0.05），产程启动时间、总产程、产时及产后2 h出血量均优于C组（P＜0.05）。无一例发生子宫破裂或宫颈撕裂。 结论 米非司酮+利凡诺中孕引产成功率高、简便、安全、副作用小，值得推广应用，其次为已烯雌酚+利凡诺中孕引产。 　　[关键词] 中孕引产；利凡诺；米非司酮；已烯雌酚 　　[中图分类号] R719.3+1 [文献标识码] B [文章编号] 1673-9701（2012）01-148-02 　　 　　Comparison of several ways of induced labor on middle pregnancy 　　SHEN Yujiao 　　Department of Obstetrics and Gynecology, Zhongshan Torch Development Zone Hospital in Guangdong Province, Zhongshan 528437, China 　　 　　[Abstract] Objective To improve the method of quantities of induced labor. Methods Selected 15 weeks to 27 weeks pregnant women, which had induced labor indications but no induced labor taboos，and had the induced labor requirements were randomized divided into Group A (mifepristone + rivanol) , group B (stilbestrol + rivanol) and group C (rivanol) . Observed the induced labor success rate, start time, total process, the bleeding of intrapartum and postnatal 2 hours, safety of three groups. Results Success rate of labor induction in group A and B group were higher than that in group C (P＜0.05) ；Process start time, total process, the bleeding of intrapartum and postnatal 2 hours in group A and B group were better than C group (P＜0.05) ；No one uterine rupture or cervical tear happen. Conclusion Mifepristone + rivanol used in induced labor are high success rate, simple, safe, small side effect, and worthy of widely clinical. The second combination is stilbestrol + rivanol. 　　[Key words] Induced labor in middle pregnancy; Rivanol; Mifepristone ; Stilbestrol 　　 　　中孕引产的困难是由中期妊娠的生理特点所决定的，尤其是孕周较小者，随着孕周的增加，对催产素的敏感性逐渐提高。利凡诺羊膜腔引产已广泛应用于临床，并已取得明确的效果，同时它的不足之处也日益显现[1]。为改进中孕引产的方法，本组对笔者所在医院近年的中孕引产者进行回顾性分析，现报道如下。 　　 　　1 资料与方法 　　1.1 一般资料 　　选择我院2009年1月～2011年9月怀孕15～27周、有引产指征而要求引产者，无引产禁忌证及药物禁忌证[1，2]，年龄16～43岁，平均25岁，中孕引产218例病例进行分析。 　　1.2 方法 　　218例患者随机分为三组，各组年龄、基础病及引产指征等差异无统计学意义，有可比性。A组：米非司酮+利凡诺80例，常规术