化学糖生物学金属离子探针宣讲培训.pptVIP

化学糖生物学;*;*;什么是化学糖生物学？;化学糖生物学主要研究内容;“预活化”一釜寡糖合成;聚合物支载的寡糖合成（包括含氟链、离子液等）;固相寡糖合成技术;酶法或化学-酶法合成寡糖;寡糖合成方法的研究;Jin-Hwan Kim, Hai Yang, Jin Park, and Geert-Jan Boons, J. Am. Chem. Soc. 2005, 127, 12090-12097.;;离去基;二、糖缀合物的合成;Chemical site-selective protein glycosylation;Chemoenzymatic approach for homogeneous N-glycoproteins;Withers, et al. Angew. Chem. Int. Ed. 2006, 45, 2585.;Chemical Synthesis of Glycopeptides and Glycoproteins;Carbohydrate Microarrays; ;;;Biosynthesis of glycans;Bioorthogonal chemical reporter strategy;Bioorthogonal chemical reactions;Cell-selective labeling based on targeted l