脓毒症发病机制及其防治研究新进展课件.pptVIP

S1PR2 signaling suppresses phagocytic function of alveolar macrophages (AMs). Part 2. Impact of S1PR2 on the regulation of macrophage phagocytosis Part 2. Conclusion Bone marrow chimeras Alveolar macrophage deletion Phagocytosis and bactericidal assay Deletion of S1PR2 in the BM-derived cells leads to increased bacterial clearance activity in the lung. Deletion of S1PR2 in AMs improves pulmonary bacterial clearance. S1PR2 deficiency enhances AMs phagocytic function. in vivo in vivo ex vivo Contents The relationship between S1PR2 and the outcome of spsis Impact of S1PR2 on the regulation of