肺癌进修医生PPT课件.ppt

放疗靶区问题 本院的2项临床II期研究(1997-2007) 均采用累及野照射(化疗后残留病灶和累及的淋巴结区) 局部失败定义为首发的除胸膜转移以外的同侧胸腔内复发及锁骨上淋巴结转移 依据失败病灶是否在PTV内区分为野内、野外失败 放疗方案 Treatment characteristics Characteristic I II Year 1997-2000 2005-2007 N 54 35 Thoracic radiotherapy regimen 56Gy/40Fx Twice daily 55Gy/22Fx Once daily Planning 2D 3D Chemotherapy(cycles) EP(4-8) EP(4-6) PCI no Patients with CR/PR 病人的一般情况 Patients characteristics Characteristic Trail I(54) II(35) Total Age(y) mean 60 54 58 range 25-70 32-77 25-77 Gender Male 48 28 76 Female 6 7 13 Performance Status(n) 0-1 50 20 70 2 4 15 19 Weight Loss(n) 0 46 27 73 10% 8 8 16