【持续性肾脏替代治疗CRRT英文精品课件】Acute Kidney Injury(91p).pptVIP

Overview of AKI Definition of AKI Pathophysiology Pre-renal Renal: glomerular, tubular, interstitial and vascular. Post renal: obstruction. Clinical features Investigations Treatment Prevention AKI Definition Sudden rapid drop in GFR, as measured by serum creatinine level, over hours to days. AKISerum Creatinine Pathophysiology AKI: Pathophysiology AKI: Prerenal “True” Volume depletion - Blood loss - GI or Renal losses Intravascular Volume Depletion Effective circulating volume depletion - Congestive heart failure - Cirrhosis - Nephrosis - Sepsis/vasodilated