从COPD治疗指南到噻托溴铵临床应用演示文稿课件.pptVIP

* * 第 30天 (稳态) * * * * * * * * 0 6 12 18 24 30 36 42 48 0 1 月 * * * * * * * * * 支气管扩张后FEV1 ? Tio vs. control = 52 – 82 mL 支气管扩张前FEV1 ? Tio vs. control = 100 – 119 mL 噻托溴铵持续4年稳定改善中度COPD患者肺功能 *P0.0001 vs. control. Repeated measure ANOVA was used to estimate means. Means are adjusted for baseline measurements. Baseline SGRQ Total Score (observed mean) = 45.035. Patients with ≥2 acceptable SGRQ Total Scores after month 6 were included in the analysis. * 噻托溴铵提高运动耐受时间 ?=228s ?=236s P=0.002 P0.001 P0.001 评价方法：6分钟步行距离 Chest， 2005;128;1168-1178 * SGRQ改善大于4分比例 S GRQ评分 异丙托溴铵 噻托溴铵 P＜0.001 P＜0.0