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Structure and function of human skin - ….doc 103页

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Text Book of Dermatology EDITOR-IN-CHIEF Xu Jinhua Department of Dermatology Huashan Hospital Fudan University CONTENTS Chapter1 Structure and function of human skin Chapter 2 Diagnosis of Skin Disease Chapter 3 Therapy in Dermatology and Venereology Chapter 4 Fungal Diseases Chapter 5 Common viral diseases of skin Chapter 6 Scabies Chapter 7 Sexually Transmitted Diseases Chapter 8 Contact Dermatitis Chapter 9 Neurodermatitis Chapter 10 Eczema Chapter 11 Urticaria Chapter 12 Drug Eruption Chapter 13 Papulosquamous dermatoses Chapter 14 Lupus Erythematosus Chapter 15 Bullous Dermatoses Chapter 16 Vitiligo Chapter 17 Acne Chapter 1 Structure and function of human skin Introduction of skin structure Human skin is a uniquely engineered organ covering the body. Being the largest organ, the skin provides around 16% of the body mass of an average person, and it covers an average area of 1.5 m2. The average thickness is 0.5-4 mm (not including subcutaneous fat tissue). The skin is thickest on the palms and soles. It is very thin on the eyelid. It performs many vital roles as both a barrier and a regulating influence between the outside world and the controlled environment within our bodies. Skin color differs by race, age, gender and location. It is darker around external genitalia, anus, and areola. The skin is composed of epidermis, dermis, subcutaneous tissue and skin appendages including hair follicles, sebaceous glands, ecrrine glands and apocrine glands, nails. There is no hair on the palms and soles, so called glabrous skin. Glabrous skin is grooved on its surface by continuously alternating ridges and sulci, in individually unique configurations known as dermatoglyphics. It is characterized by the presence of encapsulated sense organs within the dermis, and by a lack of hair follicles and sebaceous glands. Hair-bearing skin, on the other hand, has both hair follicles and sebaceous glands but lacks encapsulated sense organs. Histology o


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