18章作用于心血管系统离子通道药物.pptVIP

Cardiovascular System Overview Pharmacological treatment of cardiovascular dysfunction is directed at pathologies affecting rhythm, cardiac contractile performance, blood vessel function, or blood pressure regulation. Cardiac electrophysiology The electrical activity of each excitable cardiac cell can be measured as periodic changes in the electrical potential difference between the inside and outside of the cell. The polarity, amplitude, and pattern of change of this potential difference are determined by the transport of ions through highly regulated membrane proteins that form a variety