滋阴降火安神方治疗冠心病心律失常“阴虚火旺心神不宁”队列研究.docVIP

提 要 目的 调查中医院冠心病心律失常患者出院随访期间的终点事件发生情况，分析中医药治疗与终点事件发生情况的相关性，提供中医药治疗冠心病心律失常的循证医学证据。 方法 采用队列研究设计方法。 制作《中医医院冠心病心律失常患者队列研究调查表》。通过医院病案信息管理系统，选择山东中医药大学附属医院2008年1月1日至2013年12月31日收治的冠心病心律失常住院患者，进行病案调查。电话随访为主，结合门诊随访，随访时间设定为患者出院后3个月、6个月、1年、2年，记录患者出院后口服中成药、中药汤剂应用情况和终点事件发生情况，填入调查表随访部分。 选用Epidata 软件，建立中医医院冠心病心律失常患者队列研究随访信息数据库，录入数据，并导出数据至Excel表中。统计暴露组（应用中药≥28天者）终点事件的发生情况，多因素logistic回归分析中医药治疗与终点事件的相关性。 结果 1.随访情况 386例冠心病心律失常出院患者中，完成随访313例，失访率18.91%。平均随访时间（14.86±10.64）月66个月，最。 ABSTRACT OBJECTIVES The hospital of traditional Chinese Medicine of coronary heart arrhythmia endpoints survey follow-up of patients discharged during the occurrence, correlation analysis, to provide medical treatment of coronary heart arrhythmia evidence based medicine medical treatment and the end of the event happening. METHEDS Apply a cohort study design. Production of Chinese Medicine Hospital cohort study of patients with coronary heart arrhythmia questionnaire. Through the hospital medical record information management system, select the Affiliated Hospital of Shandong University of Traditional Chinese January 1, 2008 to December 31, 2013 hospitalized patients admitted to coronary heart arrhythmia, conduct medical record investigation. Telephone follow-up, combined with outpatient follow-up, Follow-up of patients after discharge 3 months, 6 months, 1 year, 2 years,recording oral medicine, decoction application and endpoint events occurred after the patient was discharged, the filled questionnaire follow-up section. Epidata software selection, Chinese Medicine Hospital established coronary heart arrhythmia cohort study followed up information databases, data entry, and export data to Excel table. Occurrence statistics exposure group (≥28 days by application of traditional Chinese medicine) the end of the event, the application of multivariate logistic regression analysis, correlation between medical treatment and the end of the event. RESULTS 1.Follow-up Survey of 386 cases of hospitalized patients wi