RanitidineHydrochloride(盐酸雷尼替丁)Carmustine(卡莫司汀).pptVIP

Medicinal Chemistry;Purpose ;Grading ;BOOKS; Chapter 1 Introduction;Definition of Medicinal Chemistry;1. The Scope and Purpose of MC;What is medicine?;What is medicine?;Categorizing Drugs;Enzymes and Receptors are PROTEINS;2). Research fields of MC;Appropriate administration;Preparation of drugs; Dexamethasone Acetate(醋酸地塞米松) Roussel-Uclaf, 天津天药药业有限公司 1999，cost decreases 40%， 600millions per year Market : 90% in China, 50% in the Asia；;Discovery of new drugs;High risk, High reward;RD process;Consolidation in the pharmaceutical industry;2. Origins of MC;1). Discovery(---1930);Some ancient medicinal agents still use in today;Some ancient medicinal agents still use in today ;Some ancient medicinal agents still use in today;Some ancient medicinal agents still use in today;Paul Ehrlich “Principle Chemotherapy”;2). Development(1932---1960);Prontosil (百浪多息);Development of Drugs;Accident of Development;3). Design(1960---);Design;Drugs and Targets ;;;;Achievements of PRC in Medicinal Chemistry;Artemisinin(青蒿素);3. Nomenclature of Drug Substances;Generic Name;CADN;Trade Name商品名 R; Sibutramine Hydrochloride 西布曲明;Chemical Name ;Thiamine Hydrochloride, Vitamin B1 （盐酸硫胺 ）;Thiamine Hydrochloride;Carmustine (卡莫司汀);Ranitidine Hydrochloride(盐酸雷尼替丁);Carmustine (卡莫司汀);Ranitidine Hydrochloride(盐酸雷尼替丁);Ranitidine ;Highlight points of chapter 1;Assignments