Hepatitis B Virus Nucleic Acid Amplification Technology 乙型肝炎病毒核酸扩增技术.pptVIP

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2018-06-30 发布于浙江
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Hepatitis B Virus Nucleic Acid Amplification Technology 乙型肝炎病毒核酸扩增技术.ppt

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Hepatitis B Virus Nucleic Acid Amplification Technology 乙型肝炎病毒核酸扩增技术

* * * * * * * * * * * * * * * * * * * * * * * * * * * * Indications for Cryoprecipitate No longer recommended for mild hemophilia A. It is better to use heat treated factor VIII since HIV is destroyed by heat. D.I.C Von Willebrand’s disease Massive intra-abdominal clotting in liver lacerations Fibrin glue (cryoprecipitate is mixed with thrombin and applied directly to blood vessels) * Platelets * PLATELET AGITATION AT ROOM TEMPARATURE Platelets A platelet pack contains 5.5 x 1010 platelets and can raise the platelet count 10,000 mm3 maximally. A plateletpheresis contains 3 x 1011 platelets and can raise the platelet count 30,000 mm3. * Properties of Stored Platelets Citrate Cytokines/Vasoactive Substances Indications for Platelets Prevention or arrest of bleeding in thrombocytopenic patients Maintain a platelet count 10,000 – 20,000 mm3 in medical cases Maintain a platelet count 50,000 – 100,000 mm3 in surgical cases GI bleeder who has taken aspirin Indications for Platelets Non-bleeding patient with count of 10,000/mm3 or 1x109/L Platelet count 50,000/mm3 or 5x109/L and - Bleeding due to thrombocytopenia and/or - Surgical/invasive procedure imminent Documented abnormal platelet function with bleeding or surgical/invasive procedure imminent * Platelet transfusion Do NOT transfuse platelets To patients with immune thrombocytopenic purpura (unless there is life-threatening bleeding) Prophylactically following cardiopulmonary bypass * ABO Compatible Blood Components Blood Compatible Compatible Type RBCs FFPs A A, O A, AB B B, O B, AB AB AB, A, B, O AB O O A, B, AB, O * * Editorial: Platelet ABO matters. RM Kaufman Transfusion 2009;49:5-7. ˉ PLT recovery is not the only problem with ABO-incompatible PLTs In ABO minor-incompatible PLTs, anti-A/B is passively transfused and, rarely, causes acute hemolysis PLT ABO incompatibility – major or minor – should be avoided whenever possible * ABO C