原创力文档功效的人类脐带derived-mesenchymal干细胞治疗大鼠骨髓暴露于γ辐照：（Efficacy of human umbilical cord derived-mesenchymal stem cells in treatment of rat bone marrow exposed to gamma irradiation）.pdfVIP
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Annals of Anatomy 210 (2017) 64–75
Contents lists available at ScienceDirect
Annals of Anatomy
j o u r n a l h o m e p ag e: w w w. elsev /locate/aanat
RESEARCH ARTICLE
Efficacy of human umbilical cord derived-mesenchymal stem cells in
treatment of rat bone marrow exposed to gamma irradiation
Hanaa S.E. Mousa a , Sally M. Shalaby b , Zienab A. Gouda a,∗ , Fayza E. Ahmed a ,
Aisha A. El-Khodary a
a Department of Histology and Cell Biology, Faculty of Medicine, Zagazig University, 44519 Zagazig, Egypt
b Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Zagazig University, 44519 Zagazig, Egypt
a r t i c l e i n f o a b s t r a c t
Article history: To assess the therapeutic effects of the human umbilical cord blood (hUCB) derived mesenchymal stem
Received 20 May 2016 cells (MSCs) on rat bone marrow (BM) exposed to gamma rays, 3 groups (n = 15 each) of adult male
Received in revised form Wistar albino rats were utilized as follows: the 1 st group received PBS (control group), the 2nd group
22 November 2016
was exposed to gamma rays 1.04 Gy/min (R group) and the 3rd group exposed to same dose as RG and
Accepted 6 December 2016
injected hUCB-MSCs. The BM of femurs was processed for histological and immunohistochemical stain-
ing with proliferating cell nuclear antigen antibody (PCNA), anti human CD105 and anti human CD34.
Keywords:
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