不同剂量舒芬太尼与丙泊酚及顺苯磺阿曲库铵联合应用在小儿腹腔镜手术中效果.docVIP

不同剂量舒芬太尼与丙泊酚及顺苯磺阿曲库铵联合应用在小儿腹腔镜手术中的效果 　　[摘要] 目的 探讨三种剂量舒芬太尼在患儿腹腔镜手术中麻醉效果的影响。方法 选取2014年3～11月于湖州市中心医院行腹腔镜手术的患儿61例，随机分成A、B、C组，分别给予舒芬太尼0.3、0.4、0.5 μg/kg并联合丙泊酚及顺苯磺阿曲库铵进行麻醉诱导；术中根据患儿情况，可追加0.01 μg/mL的舒芬太尼。比较各组间舒芬太尼使用情况、麻醉效果、心血管指标变化情况以及不良反应。 结果 C组舒芬太尼使用量显著高于B组（P 0.05）。三组患儿麻醉后，平均动脉压（MAP）、收缩压（SBP）、舒张压（DBP）、心率（HR）与各自基础值比较均显著降低（P 0.05）。A组的术中患儿的MAP、SBP、DBP与基础值比较均显著升高，差异有统计学意义（P 0.05）；术中B组和C组患儿的MAP、SBP、DBP、HR值与基础值比较，差异均无统计学意义（P 0.05）。随着舒芬太尼使用量的增加，肢体反应率逐渐降低（P 0.05）。 结论 在患儿腹腔镜手术中，0.5 μg/kg舒芬太尼使用量在联合丙泊酚和顺苯磺阿曲库铵行麻醉诱导时能具有稳定的血流动力学，较少的不良反应以及较高的麻醉有效率。 　　[关键词] 舒芬太尼；腹腔镜手术；麻醉 　　[中图分类号] R726.1 [文献标识码] A [文章编号] 1673-7210（2015）06（a）-0141-04 　　Effect of different doses of Sufentanil combined with Propofol and Cisa-tracurium Besylate in children laparoscopic surgery 　　HU Xiaobin YU Liang 　　Department of Anesthesiology， Huzhou Central Hospital， Zhejiang Province， Huzhou 313000， China 　　[Abstract] Objective To investigate the effect of three doses of Sufentanil anesthesia in children laparoscopic surgery. Methods From March to November 2014， in Huzhou Central Hospital， 61 children underwent laparoscopic operation were selected and randomly divided into group A， B， C， these groups were given Sufentanil 0.3， 0.4， 0.5 μg/kg respectively and combined with Propofol and Cisatracurium Besylate for induction of anesthesia； according to the operation condition， it can be added 0.01 μg/mL Sufentanil. The Sufentanil usage， anesthesia， cardiovascular index changes and adverse reactions of three groups were compared. Results The amount of Sufentanil in group C was significantly higher than that in group B （P 0.05）. After anesthesia， MAP， SBP， DBP， HR in three groups were decreased than the baseline values （P 0.05）. During the surgery， MAP， SBP， DBP in group were higher than the baseline values， the differences were statistically significant （P 0.05）； during the surgery， MAP， SBP， DBP， HR in group B and C were compared with the baseline values， the differences were not statistically significant （P