不同时期不孕症患者激素水平变化对比研究.docVIP

不同时期不孕症患者激素水平变化的对比研究 　　【摘 要】 目的：探究不同时期不孕症患者的性激素水平变化情况，为临床不孕症的诊疗提供依据。方法：研究对象选取为2014.1～2015.1之间我院收治的80例不孕症患者，分为卵泡期33例，排卵期24例，黄体期23例，选取同期健康体检女性104例作为对照，同样根据分为卵泡期41例，排卵期34例，黄体期29例，分别对两组患者进行卵泡刺激素（follicle-stimulating hormone，FSH）、黄体生成素（luteinizing hormone，LH）、雌二醇（Estradiol，E2）、垂体泌乳素（prolactin，PRL）、孕酮（Progesterone，P）、睾酮（Testosterone，T）6项激素水平检测，并对检测结果进行对比分析。结果：卵泡期不孕症患者的FSH、E2、PRL、P、T水平与对照组相比存在显著差异（P0.05）；排卵期不孕症患者的FSH、LH、E2、P、T水平与对照组相比存在显著差异（P0.05）；黄体期不孕症患者的LH、PRL、P水平与对照组相比存在显著差异（P0.05）。结论：性激素水平的变化与女性不孕症的发生有密切相关，且随着月经周期的变化存在一定差异，针对性的检验可以作为不孕症诊断和治疗的相关依据。 　　【关键词】 不孕症 性激素水平 对比研究 　　【Abstract】 Objective： to explore the sex hormone levels of infertility patients in different periods and to provide basis for clinical diagnosis and treatment of infertility.Methods： the research object to choose between 2014.1 ～ 2015.1， our hospital 80 cases of infertility patients were divided into follicular phase 33 cases， 24 cases of ovulation and luteal phase 23 cases， choose the health physical examination， 104 cases of women for the same period as the control， according to the same can be divided into follicular phase， 41 cases of ovulation 34 cases， luteal phase 29 cases， respectively on two groups of patients with FSH， LH， E2， PRL and P， T hormone level detection， and the testing results were analyzed.Results： the follicular phase of infertility patients FSH， E2， PRL and P， T level significant differences compared with control group （P 0.05）；Ovulation infertility patients of FSH， LH， E2， P， T level significant differences compared with control group （P 0.05）；Luteal phase infertility LH， PRL and P level in patients with significant differences compared with control group （P 0.05）.Conclusion： the changes of sex hormone level is closely related with the incidence of female infertility， and as the change of the menstrual cycle， there exist certain differences of inspection can be used as the relevant basis of diagnosis and treatment of infertility. 　　【Key words】 infertility；Sex hormone