石菖蒲化学成分和其对中枢神经系统作用研究 进展.pdf

Pharmacy Information 药物资讯, 2017, 6(5), 133-141 Published Online November 2017 in Hans. /journal/pi /10.12677/pi.2017.65022 Research Progress on Chemical Constituents of Acorus tatarinowii schott and Their Pharmacological Activities on Central Nervous System * # Jie Yang , Rujun Tao, Yinyun Wang, Feifei Lei, Shaozhong Luo School of Pharmaceutical Sciences and Yunnan Provincial Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming Yunnan th st th Received: Nov. 9 , 2017; accepted : Nov. 21 , 2017; published: Nov. 29 , 2017 Abstract The main chemical constituents of Acorus tatarinowii schott included essential oil, alkaloids, qui- nones, amino acid and sugars. Their pharmacological effects on the central nervous system cov- ered sedation, anti-convulsion, anti-epilepsy, anti-depression, anti-senile dementia, nervecell protection, and so forth. The clinical research and application has been paid much attention. This work reviews its recent study about the main chemical constituents and effects on the central nervous system. Keywords Acorus tatarinowii schott, Chemical Constituents, Central Nervous System 石菖蒲化学成分及其对中枢神经系统作用研究 进展 * # 杨 洁 ，陶汝俊，王垠芸，雷菲菲，罗绍忠 昆明医科大学暨云南省天然药物药理重点实验室，云南 昆明 收稿日期：2017年11月9 日；录用日期：2017年11月21 日；发布日期：2017年11月29 日 *第一作者。 #通讯作者。 文章引用: 杨洁, 陶汝俊, 王垠芸, 雷菲菲, 罗绍忠. 石菖蒲化学成分及其对中枢神经系统作用研究进展[J]. 药物资 讯, 2017, 6(5): 133-141. DOI: 10.12677/pi.2017.65022 杨洁 等 摘 要 石菖蒲主要的化学成分有挥发油、生物碱及醌类、氨基酸和糖类以及其它类成分，石菖蒲对中枢神经系 统的作用主要有镇静、抗惊厥、抗癫痫、抗抑郁、预防和治疗痴呆症、神经细胞保护作用等，石菖蒲的