第七课：肝癌预后危险因素.docVIP

clinicopathological factors Age ≤65 65 Sex M F Presentation Subclinical Symptomatic Hepatitis B surface antigen Positive Negative Hepatitis C antibody Positive Negative Dual infection Positive Negative Child classification Grade A Grade B Preoperative ICG R-15 min (%) ≤15 15 Serum Urea nitrogen (mg/dl) ≤21 21 Serum Creatinine (mg/dl) ≤1.4 1.4 Serum Albumin (g/dl) ≤3.5 3.5 Serum Alkaline phosphatase (U/L) ≤94 94 Serum Aspartate aminotransferase (U/L) ≤34 34 Serum Alanine aminotransferase (U/L) ≤36 36 Serum Total bilirubin (mg/dl) ≤2.0 2.0 Platelet count (≤109/L) ≤150 150 Prothrombin time/prolong (s) ≤4.0 4.0 Extent of resection（Type of resection） Major hepatectomy Minor hepatectomy Major resection is defined as resection of ≥ three segments, minor resection as resection of ≤ two segments. Blood loss (L) ≤4 4 Blood transfusion No Yes Morbidity No Yes AFP ≤20 20 Rupture No Yes Tumor size (cm) ≤2？5？ 2？5？ Satellite lesions None Yes Resection margin (cm) ≤1 1 Capsular formation Positive Negative Capsular invasion No Yes Vascular invasion No Yes Diploidy status Yes No Tumor number Solitary Multiple Macroscopic resection margin ≤1 cm ＞1 cm Microscopic resection margin Positive Negative Microscopic venous invasion No Yes Tumor encapsulation No Yes pTNM stage≈ I II IIIA IVA Abbreviation: pTNM stage, pathologic tumor-node-metastasis stage.addin KingyeeNoteReferenceIReferenceIDRefTypeID00002/RefTypeIDTitleTNM Classification of Malignant Tumours (ed 5)/TitleTitleTrans/TitleTransSecondTitleNew York, NY, John Wiley/SecondTitlePYear1997/PYearSubAuthor/SubAuthorAuthorSobin LH, Wittekind C/AuthorSdyAuthor/SdyAuthorTtyAuthor/TtyAuthorVolume/VolumeNumVolume/NumVolumeIssue/IssuePages/PagesPubDate/PubDatePlacePub/PlacePubPublisher/PublisherEdition/EditionTertiaryTitle/TertiaryTitleTypeWork/TypeWork/KingyeeNote 1 对于乙肝患者而言，术前HBV-DNA水平的影响很重要！ 此外，肝硬化、肝纤维化程度的影响！ The following clinicopathologic variables that might correlate with disease-free survival and recurrence rates were eva