“加味四君子汤”对增龄大鼠免疫系统的调节作用及初步机制探讨老年医学专业论文.docxVIP

华 华 中 科 技 大 学 硕 士 学 位 论 文 PAGE 5 PAGE 5 compared with the positive control group, drug group were significantly lower in IgG level of (P0.05). (3) rats thymus index and spleen index in comparison: compared with the young control group, the older the group, thymus and spleen index were significantly lower (P0.01); compared with the aged control group, drug group thymus index was significantly higher (P0.01), spleen index was no significant difference (P0.05), positive control group thymus index were significantly higher (P0.01), spleen index was no significant difference (P0.05); compared with drug group and the positive control group, the thymus index and spleen index were not significant different (P0.05). (4) Rats thymus, spleen Morphological comparison: Drug group thymus had varying degrees of atrophy, reduce thymus pathological changes is the degree of fat substitution, more frequent distribution of thymus cells, coloring is good. Compared with the aged control group, treatment group spleen white pulp and red pulp of the boundaries less clear, a slight increase in white pulp, increase in the number of neutrophils, lymphocytes arranged loosely. (5) the expression of thymus IL-2 levels: compared with the young control group, the rats aged thymus expression of IL-2 were significantly lower (P0.01); compared with the aged control group, drug group thymus IL -2 expression was increased (P0.01), positive control thymic expression of IL-2 levels (P0.01); compared with drug group and the positive control group, IL-2 expression in the thymus was no significant difference (P0.05). (6) the expression of splenic TNF-α levels: compared with the young control group, the rats aged spleen expression of TNF-α were significantly higher (P0.01); compared with the aged control group, treatment group spleen TNF-α expression levels decreased (P0.01), positive control spleen TNF-α expression levels decreased (P0.01); compared with drug group and the positive control group, the sple