左炔诺孕酮宫内缓释系统对子宫腺肌病患者痛经影响.docVIP

左炔诺孕酮宫内缓释系统对子宫腺肌病患者痛经影响 　　[摘要] 目的 观察左炔诺孕酮宫内缓释系统治疗子宫腺肌病痛经的临床效果。方法 选择我院2015年3月～2016年3月68例子宫腺肌病痛经患者，根据治疗方法分为观察组（36例）与对照组（32例），对照组以孕三烯酮进行治疗，观察组以左诀诺孕酮宫内缓释系统进行治疗，观察两组患者的子宫内膜厚度、子宫体积、痛经评分、月经经期时间、血红蛋白、血清CA125、激素水平以及临床疗效和不良反应。结果 观察组患者子宫内膜厚度以及子宫体积改善情况明显优于对照组（P0.05）；观察组患者痛经评分、月经经期时间改善情况明显优于对照组（P0.05）；两组血红蛋白较治疗前上升（P0.05），并渐至正常水平，血清CA125水平治疗后明显下降（P0.05），且观察组优于对照组。结论 以左炔诺孕酮宫内缓释系统对子宫腺肌病痛经进行治疗，能够使患者子宫内膜厚度以及子宫体积得到显著改善，改善痛经症状，安全性好。 　　[关键词] 左炔诺孕酮宫内缓释系统；子宫腺肌病；痛经；孕三烯酮 　　[中图分类号] R711.51 [文献标识码] A [文章编号] 2095-0616（2017）16-72-03 　　The effects of levonorgestrel-releasing intrauterine system on dysmenorrhea of patients with adenomyosis of the uterus 　　ZHANG Fengjuan 　　Maternal and Child Health Care Family Planning Service Center of Zhangdian District of Zibo City， Zibo 255043， China 　　[Abstract] Objective To observe the clinical effect of levonorgestrel-releasing intrauterine system on dysmenorrhea of patients with adenomyosis of the uterus. Methods From March 2015 to March 2016， 68 patients with adenomyosis of the uterus were selected. According to the treatment method， the patients were divided into observation group （36 cases） and the control group （32 cases）. The patients in control group were treated with trienone， and the patients in the observation group were treated with levonorgestrel-releasing intrauterine system. The endometrial thickness， uterine volume， dysmenorrhea score， menstrual cycle time， hemoglobin， serum CA125， hormone levels， and clinical efficacy and adverse reactions were observed in both groups. Results The endometrial thickness and the improvement of uterine volume in the observation group were significantly better than that in control group（P0.05）. The improvement of pain score and menstrual cycle time in the observation group were significantly better than that in the control group（P0.05）. The hemoglobin of two groups were ascending before treatment（P0.05）， and the serum CA125 level was significantly decreased（P0.05）， and the CA125 level in observation grou