联合检测胸腔积液ADAIL―27T―SPOT TB对结核性胸膜炎诊断价值.docVIP

联合检测胸腔积液ADAIL―27T―SPOT TB对结核性胸膜炎诊断价值 　　[摘要] 目的 评价胸腔积液腺苷脱氨酶（ADA）白介素-27（IL-27）、T-SPOT TB对结核性胸膜炎的诊断价值。 方法 方便选取2016年10月―2017年5月收治的40例结核性胸膜炎患者作为观察组，35例恶性胸腔积液患者作为对照组，两组患者均予抽取胸腔积液，检测两组胸腔积液中ADA、IL-27水平及T-SPOT TB阴性、阳性结果。 结果 结核性胸膜炎患者胸腔积液ADA（67.83±20.31）U/L、IL-27（420.15±65.27）ng/L水平明显高于恶性胸腔积液组ADA（27.52±12.47）U/L、IL-27（136.78±34.19）ng/L，差异有统计学意义（t=1.78、1.92，P0.05），T-SPOT TB阳性率明显高于恶性胸腔积液患者，差异有统计学意义（χ2=43.28，P0.05）。 结论 联合检测胸腔积液ADA、IL-27、T-SPOT TB对结核性胸膜炎的诊断具有重要价值 　　[关键词] 胸腔积液；结核性胸膜炎；恶性胸腔积 　　[中图分类号] R541.4 [文献标识码] A [文章编号] 1674-0742（2018）02（c）-0028-03 　　Diagnostic Value of Combined Detection of Pleural Effusion ADA， IL-27 and T-SPOT TB in Tuberculous Pleurisy 　　TANG Guan-jun1， ZHANG Yan-li2 　　1.Respiratory Medicine Department， Xushui People’s Hospital， Baoding， Hebei Province， 071000 China； 2.Hebei Province Infectious Diseases Hospital， Baoding， Hebei Province， 071000 China 　　[Abstract] Objective This paper tries to evaluate the diagnostic value of pleural effusion adenosine deaminase （ADA） interleukin-27 （IL-27） and T-SPOT TB in tuberculous pleurisy. Methods 40 patients with tuberculous pleurisy admitted from October 2016 to May 2017 were enrolled as observation group and 35 patients with malignant pleural effusion as control group. Pleural effusion was extracted from both groups， and pleural effusion ADA， IL-27 levels and T-SPOT TB negative， positive results. Results The levels of ADA（67.83±20.31）U/L and IL-27（420.15±65.27）ng/L in patients with tuberculous pleurisy were significantly higher than those in patients with malignant pleural effusion ADA（27.52±12.47）U/L， IL-27 （136.78±34.19）ng/L. The difference was statistically significant（t=1.78，1.92，P0.05）. The positive rate of T-SPOT TB in patients with malignant pleural effusion was significantly higher than that in patients with malignant pleural effusion. The difference was statistically significant （χ2=43.28， P0.05）. Conclusion Combined detection of pleural effusion ADA， IL-27 and T-SPOT TB is of great value in the diag