肝动脉化疗栓塞治疗肝癌合并门静脉癌栓效果分析.docVIP

肝动脉化疗栓塞治疗肝癌合并门静脉癌栓效果分析 　　[摘要] 目的 观察肝动脉化疗栓塞（TACE）治疗肝癌合并门静脉癌栓（PVTT）的效果。 方法 选取本院2010年3月～2012年3月收治的经CT/MRI证实的肝癌合并PVTT患者147例，其中65例进行单纯手术治疗，设为对照组，其余82例在术后接受TACE治疗，设为观察组。比较两组患者0.5、1、2、3年的生存率，生存时间和无瘤生存时间。 结果 观察组患者0.5、1、2、3年的生存率均明显高于对照组，生存时间、无瘤生存时间均明显长于对照组，组间差异有统计学意义（P0.05）。 结论 肝癌合并PVTT患者在术后予以TACE治疗可显著提高患者的生存率，延长其生存时间，值得临床推广应用。 　　[关键词] 肝动脉化疗栓塞；肝癌；门静脉癌栓 　　[中图分类号] R735.7 [文献标识码] A [文章编号] 1674-4721（2015）05（b）-0068-03 　　Effect analysis of transcatheter arterial chemoembolization in the treatment of liver cancer complicated with portal vein tumor thrombus 　　YANG Hai 　　Department of Intervention，the Fist Affiliated Hospital of Henan University of Science and Technology，Luoyang 471000，China 　　[Abstract] Objective To observe the effect of transcatheter arterial chemoembolization （TACE） in the treatment of liver cancer complicated with portal vein tumor thrombus （PVTT）. Methods 147 patients with liver cancer complicated with PVTT confirmed by CT/MRI treated in our hospital from March 2010 to March 2012 were selected，among them，65 patients were given simple operation treatment and selected as control group，while the other 82 patients were given TACE treatment after operation and selected as observation group.Survival rate of 0.5，1，2，3 years and survival time，survival time without tumor between two groups was compared respectively. Results Survival rate of 0.5，1，2，3 years in observation group was obviously higher than that of control group respectively，and survival time and survival time without tumor in in observation group was obviously longer than that of control group respectively，and there was a statistical difference between two groups （P0.05）. Conclusion For patients with liver cancer complicated with portal vein tumor thrombus，TACE applied after surgery can improve survival rate and prolong survival time of patients.It is worthy of clinical popularization and application. 　　[Key words] Transcatheter arterial chemoembolization；Liver cancer；Portal vein tumor thrombus