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Age differences in presentation, diagnosis pathway and management of colorectal cancer 标题：结直肠癌在不同年龄段临床表现、诊断途径及管理方法上的差异 作者：Magdalena Esteva , Amador Ruiz , Maria Ramos , Monserrat Casamitjana 作者单位：Unit of Research, Majorca Department of Primary Health Care, Balearic Institute of Health, Reina Esclaramunda 9, 07003 Palma de Mallorca, Spain Majorca Cancer Registry, Department of Public Health, Balearic Department of Health, C/Jesu′s n 33, 07001 Palma de Mallorca, Spain Health Consorcium of Barcelona, Parc Sanitari Pere Virgili – Edifici Mestral, Esteve Terrades, 30, 08023 Barcelona, Spain * Abstract Introduction Methods Results Discussion References Abstract 背景、方法、结果 Background: The gap in survival between older and younger European cancer patients is getting wider. It is possible that cancer in the elderly is being managed or treated differently than in their younger counterparts. This study aims to explore age disparities with respect to the clinical characteristics of the tumour, diagnostic pathway and treatment of colorectal cancer patients. Methods: We conducted a multicenter cross sectional study in 5 Spanish regions. Consecutive incident cases of CRC were identified from pathology services. Measurements: From patient interviews, hospital and primary care clinical records, we collected data on symptoms, stage, doctors investigations, time duration to diagnosis/treatment, quality of care and treatment. Results: 777 symptomatic cases, 154 were older than 80 years. Stage was similar by age group. General symptoms were more frequent in the eldest and abdominal symptoms in the youngest. No differences were found regarding perception of symptom seriousness and symptom disclosure between age groups as no longer duration to diagnosis or treatment was observed in the oldest groups. In primary care, only ultrasound is more frequently ordered in those 65 years. Those 80 years had a significantly higher proportion of iron testing and abdominal XR requested in hospital.