单用二氧化碳激光与联合重组人α2b干扰素治疗尖锐湿疣80临床疗效观察.docVIP

单用二氧化碳激光与联合重组人α2b干扰素治疗尖锐湿疣80临床疗效观察 　　【摘要】目的 探讨二氧化碳（CO2）激光和激光联合重组人α-2b干扰素治疗尖锐湿疣的临床疗效对比分析。方法 选自我院2009年3月～2011年6月收治的80例尖锐湿疣患者，随机分为A对照组和B干扰素组。A组40例，单用激光治疗，B组40例采用CO2激光联合重组人α-2b干扰素治疗，所有患者均随访6个月。结果 A组痊愈10例，显效21例，有效7例，无效2例，，B组痊愈16例，显效19例，有效5例，无效0例，结论 笔者认为CO2激光联合重组人α-2b干扰素局部注射治疗尖锐湿疣，操作简便、灵活、创面深浅易控制，具有疗效满意、复发率低的优势，值得临床推广应用。 　　【关键词】人类乳突病毒（HPV） 尖锐湿疣 二氧化碳（CO2）激光 重组人α-2b干扰素 复发 临床治疗 　　中图分类号：R752.53文献标识码：A文章编号：1005-0515（2011）12-029-02 　　Single-use carbon dioxide (CO2) laser and the United recombinant human interferon α-2b Clinical efficacy of treatment of genital warts 80 　　LI Furong 　　（CDC Jintang County, Chengdu, Sichuan Province, Chengdu 610400） 　　【Abstract】Objective To investigate the carbon dioxide (CO2) laser and laser and recombinant human interferon α-2b treatment of genital warts compared the clinical efficacy analysis. Methods selected from our hospital in March 2009 - June 2011 were treated 80 cases of genital warts were randomly divided into A group and B interferon group. A group of 40 patients, laser treatment alone, B group of 40 patients using CO2 laser and recombinant human interferon α-2b treatment, all patients were followed up for 6 months. Results A group cured 10 cases, 21 cases markedly effective in 7 cases, 2 cases, B group recovered in 16 cases, 19 cases were markedly effective in 5 cases, 0 cases, the Conclusion I believe that the CO2 laser combined with recombinant human α-local injection of interferon-2b treatment of genital warts, simple, flexible, easy to control the depth of the wound with a satisfactory outcome, the advantage of low recurrence rate, worthy of clinical application. 　　【Key words】human papillomavirus (HPV) genital warts carbon dioxide (CO2) laser recombinant human interferon α-2b recurrence clinical treatment 　　人类乳突病毒（Human Papillomavirus，HPV）是一种Papillomavirus科的DNA病毒，主要类型为HPV1、2、6、11、16、18、31、33及35型等，其中HPV16和18型长期感染可能与女性宫颈癌的发生有关。人类乳突病毒主要感染人类的皮肤和表层黏膜。有高度的特异性，生长在生殖器官上或附近皮肤、粘膜上的人类寻常疣为尖锐湿疣。临床症状为表面凹凸不平，湿润柔软，呈乳头样，蕈样或菜花样突起，红色或污灰色，根部